Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 14/20 | 0.45 |
| ▸ | PYGM | P11217 | 14/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045340 | 0.86 | PYGL (0.36) | PYGLPYGMLMNAL3MBTL1ADORA2B | |
| SCHEMBL8082470 | 0.79 | ALOX15 (0.51) | PYGLPYGMLMNAL3MBTL1ADORA2B | |
| SCHEMBL8081791 | 0.76 | PYGL (0.44) | PYGLPYGMLMNAL3MBTL1ADORA2B | |
| SCHEMBL8080963 | 0.74 | KMT2A (0.47) | PYGLPYGMLMNAL3MBTL1ADORA2B | |
| SCHEMBL10653191 | 0.73 | PYGL (0.53) | PYGLPYGMLMNAALOX15ALDH1A1 | |
| SCHEMBL7275567 | 0.72 | PYGL (0.49) | PYGLPYGMLMNAALDH1A1 | |
| SCHEMBL9047294 | 0.69 | ALOX15 (0.40) | PYGLPYGMLMNAL3MBTL1ALOX15 | |
| SCHEMBL9770221 | 0.69 | PYGM (0.52) | PYGLPYGMLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9658365 | 0.69 | PYGL (0.42) | PYGLPYGMLMNAALOX15ALDH1A1 | |
| SCHEMBL8080875 | 0.69 | ADORA2B (0.41) | PYGLPYGMLMNAADORA2BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121284-A | SPECIFIED 1-(ALKYL OR CYCLOALKYL)-2-METHYL-3-(ALKOXYCARBONYL)-4-(SUBSTITUTED PYRIDYL OR ARYL)-5-OXO-1,4,5,6,7,8-HEXAHYDROQUINOLINE COMPOUNDS; TREATING SICKLE CELL ANEMIA, PSYCHOSES, DEPRESSION | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |