Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9051872 | 0.99 | GSK3A (0.46) | GSK3AGSK3BNAMPTPKMPOLB | |
| SCHEMBL9048823 | 0.91 | GSK3A (0.47) | GSK3AGSK3BNAMPTPKMPOLB | |
| Hydrochloric Acid SCHEMBL9051878 | 0.90 | GSK3A (0.46) | GSK3AGSK3BNAMPTPKMPOLB | |
| SCHEMBL6851321 | 0.87 | HPGD (0.48) | POLBHPGDNPC1RAB9AKMT2A | |
| Fumaric Acid SCHEMBL7334141 | 0.82 | HPGD (0.43) | HPGDNPC1RAB9AKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL9050917 | 0.80 | HTR3A (0.39) | HPGDALDH1A1LMNA | |
| SCHEMBL9050448 | 0.78 | TRPV1 (0.47) | POLBALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7333785 | 0.77 | MMP8 (0.47) | POLBHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL7327986 | 0.76 | L3MBTL1 (0.47) | PKMALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL7325548 | 0.76 | SMN1; SMN2 (0.45) | POLBALDH1A1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381422-B1 | Tetrahydrobenzimidazole derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-10-23 | — | — | EP | claimed |
| US-5344927-A | 5-HT3 antagonist | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |