Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052649 | 0.91 | DRD2 (0.54) | DRD2DRD3TAS2R14ALDH1A1LMNA | |
| SCHEMBL8545748 | 0.89 | ALDH1A1 (0.54) | DRD2DRD3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8540116 | 0.82 | L3MBTL1 (0.55) | DRD2DRD3ALDH1A1SMN1; SMN2PDE4A | |
| SCHEMBL9053373 | 0.78 | DRD2 (0.50) | DRD2DRD3ALDH1A1LMNAHTT | |
| SCHEMBL8544314 | 0.78 | MAPT (0.54) | DRD2DRD3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9053438 | 0.78 | SMN1; SMN2 (0.51) | DRD2DRD3ALDH1A1LMNATSHR | |
| SCHEMBL8544972 | 0.77 | DRD2 (0.56) | DRD2DRD3 | |
| SCHEMBL9049088 | 0.75 | TAS2R14 (0.62) | TAS2R14ALDH1A1LMNASMN1; SMN2PDE4A | |
| SCHEMBL9053622 | 0.73 | DRD2 (0.50) | DRD2DRD3LMNASMN1; SMN2KDM4E | |
| SCHEMBL7204676 | 0.72 | ALDH1A1 (0.77) | ALDH1A1LMNATSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |