Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053039 | 0.91 | PGR (0.51) | DRD2DRD3KDM4ELMNAMAPT | |
| SCHEMBL9053185 | 0.91 | MAPT (0.50) | DRD2DRD3KDM4ELMNAMAPT | |
| SCHEMBL9051914 | 0.90 | MAPT (0.42) | DRD2DRD3KDM4ELMNAMAPT | |
| SCHEMBL9115693 | 0.90 | FFAR1 (0.46) | DRD2DRD3KDM4ELMNAMAPT | |
| SCHEMBL9053598 | 0.87 | SIRT2 (0.46) | DRD2DRD3KDM4ELMNAMAPT | |
| SCHEMBL9053693 | 0.87 | CYP11B1 (0.44) | DRD2DRD3KDM4ELMNAMAPT | |
| SCHEMBL8544314 | 0.86 | MAPT (0.54) | DRD2DRD3KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9053438 | 0.85 | SMN1; SMN2 (0.51) | DRD2DRD3KDM4ELMNAMAPT | |
| SCHEMBL9054157 | 0.85 | DRD2 (0.41) | DRD2DRD3LMNAATMKMT2A | |
| SCHEMBL9053373 | 0.84 | DRD2 (0.50) | DRD2DRD3KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |