Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053622 | 0.85 | DRD2 (0.50) | DRD2DRD3ATMLMNAKMT2A | |
| SCHEMBL8544314 | 0.83 | MAPT (0.54) | DRD2DRD3ALDH1A1MEN1KMT2A | |
| SCHEMBL9053358 | 0.82 | PSEN1 (0.43) | DRD2DRD3ALDH1A1LMNANPSR1 | |
| SCHEMBL9053039 | 0.81 | PGR (0.51) | DRD2DRD3ALDH1A1LMNAKMT2A | |
| SCHEMBL9051914 | 0.80 | MAPT (0.42) | DRD2DRD3ALDH1A1LMNAMEN1 | |
| SCHEMBL9115693 | 0.80 | FFAR1 (0.46) | DRD2DRD3ALDH1A1LMNANPSR1 | |
| SCHEMBL9060714 | 0.79 | ALDH1A1 (0.39) | DRD2DRD3ALDH1A1LMNANPSR1 | |
| SCHEMBL9053373 | 0.79 | DRD2 (0.50) | DRD2DRD3ALDH1A1LMNAMEN1 | |
| SCHEMBL8545748 | 0.78 | ALDH1A1 (0.54) | DRD2DRD3ALDH1A1LMNAMEN1 | |
| SCHEMBL9053598 | 0.78 | SIRT2 (0.46) | DRD2DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |