Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053039 | 0.90 | PGR (0.51) | DRD2DRD3KMT2AMAPTLMNA | |
| SCHEMBL9053622 | 0.90 | DRD2 (0.50) | DRD2DRD3KMT2AMAPTLMNA | |
| SCHEMBL9051914 | 0.89 | MAPT (0.42) | DRD2DRD3KMT2AMAPTLMNA | |
| SCHEMBL9053598 | 0.86 | SIRT2 (0.46) | DRD2DRD3MAPTLMNAPGR | |
| SCHEMBL9053358 | 0.86 | PSEN1 (0.43) | DRD2DRD3MAPTLMNANPSR1 | |
| SCHEMBL8544314 | 0.83 | MAPT (0.54) | DRD2DRD3KMT2AMAPTHTT | |
| SCHEMBL9053693 | 0.82 | CYP11B1 (0.44) | HSD17B10HPGDDRD2DRD3KMT2A | |
| SCHEMBL9053185 | 0.81 | MAPT (0.50) | DRD2DRD3KMT2AMAPTLMNA | |
| SCHEMBL9054157 | 0.80 | DRD2 (0.41) | HPGDDRD2DRD3KMT2ALMNA | |
| SCHEMBL8545748 | 0.78 | ALDH1A1 (0.54) | DRD2DRD3KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |