SCHEMBL905562

SCHEMBL905562

CCCS(=O)(=O)ON1CCOCC1.[NaH]

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
LMNA P02545 4/20 0.38
CYP1A2 P05177 1/20 0.35
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 6/20 0.34
MAPT P10636 1/20 0.34
POLB P06746 1/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RECQL P46063 1/20 0.32
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546851 0.98 ALDH1A1 (0.39) ALDH1A1LMNACYP1A2CA12CA7
SCHEMBL465060 0.87 LMNA (0.39) ALDH1A1LMNACYP1A2CA12CA7
SCHEMBL27424013 0.86 CA12 (0.38) ALDH1A1LMNACA12CA7CA14
SCHEMBL28519204 0.86 L3MBTL1 (0.32) L3MBTL1
SCHEMBL27669796 0.86 CA12 (0.41) ALDH1A1LMNACA12CA7CA14
Water SCHEMBL27165203 0.85 CA12 (0.37) ALDH1A1LMNACA12CA7CA14
SCHEMBL28752430 0.84 THRB (0.38) ALDH1A1LMNACYP1A2SMN1; SMN2POLB
SCHEMBL465094 0.84 CA12 (0.39) ALDH1A1LMNACA12CA7CA14
SCHEMBL28463231 0.84 L3MBTL1 (0.33) ALDH1A1LMNATSHRMAPTPOLB
Water SCHEMBL27714982 0.82 CA12 (0.38) ALDH1A1LMNACA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113447585-B Method for evaluating quality of liquid for in-vitro assisted reproduction based on liquid chromatography 中国食品药品检定研究院 2022-03-15 CN claimed
CN-113447585-A Method for evaluating quality of liquid for in-vitro assisted reproduction based on liquid chromatography 中国食品药品检定研究院 2021-09-28 CN claimed
US-11478799-B2 Method for conducting reactions involving biological molecules in plugs in a microfluidic system THE UNIVERSITY OF CHICAGO (US) 2022-10-25 US disclosed
EP-2283918-B1 Device and method for pressure-driven plug transport and reaction UNIV CHICAGO (US) 2022-10-05 EP disclosed
EP-2282214-B1 Device and method for pressure-driven plug transport and reaction UNIV CHICAGO (US) 2022-10-05 EP disclosed
US-11413615-B2 Device and method for pressure-driven plug transport and reaction THE UNIVERSITY OF CHICAGO (US) 2022-08-16 US disclosed
US-11413614-B2 Device and method for pressure-driven plug transport and reaction THE UNIVERSITY OF CHICAGO (US) 2022-08-16 US disclosed
EP-3290921-B1 DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION UNIV CHICAGO (US) 2022-06-15 EP disclosed
CN-114591266-A Preparation process of compound containing sulfonic group 苏州亚科科技股份有限公司 2022-06-07 CN disclosed
CN-112582564-B Light emitting device and method of manufacturing the same TCL科技集团股份有限公司 2022-04-08 CN disclosed
US-11278898-B2 Method for conducting an autocatalytic reaction in plugs in a microfluidic system THE UNIVERSITY OF CHICAGO (US) 2022-03-22 US disclosed
US-20100233026-A1 DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION ISMAGLIOV RUSTEM F 2010-09-16 US disclosed
EP-1508044-B1 DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION UNIV CHICAGO (US) 2010-09-01 EP disclosed
EP-1508044-A4 DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION UNIV CHICAGO (US) 2008-09-10 EP disclosed
US-20070172954-A1 Device and method for pressure-driven plug transport and reaction THE UNIVERSITY OF CHICAGO 2007-07-26 US disclosed
US-7129091-B2 Microfluidic systems; improved control over mass and heat transport; merge one or more plug fluids UNIVERSITY OF CHICAGO (US) 2006-10-31 US disclosed
US-20050272159-A1 DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION UNIVERSITY OF CHICAGO, THE 2005-12-08 US disclosed
US-20050087122-A1 Device and method for pressure-driven plug transport and reaction THE UNIVERSITY OF CHICAGO 2005-04-28 US disclosed
EP-1508044-A2 DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION The University of Chicago (US) 2005-02-23 EP disclosed
WO-2004038363-A2 MICROFLUIDIC DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION THE UNIVERSITY OF CHICAGO (US) 2004-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11278898-B2 Method for conducting an autocatalytic reaction in plugs in a microfluidic system POR, DCXR, SLCO4C1 ALDH1A1 1470/4885LMNA 2468/4885CYP1A2 373/4885
US-11413615-B2 Device and method for pressure-driven plug transport and reaction SLC6A9, SLC6A5, PTGFR ALDH1A1 3721/4885LMNA 3079/4885CYP1A2 2271/4885
US-11478799-B2 Method for conducting reactions involving biological molecules in plugs in a microfluidic system SLCO4C1, C3AR1, MSN ALDH1A1 1331/4885LMNA 2766/4885CYP1A2 1111/4885
US-11413614-B2 Device and method for pressure-driven plug transport and reaction SLC6A9, SLC6A5, PTGFR ALDH1A1 3721/4885LMNA 3079/4885CYP1A2 2271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.