SCHEMBL9065775

SCHEMBL9065775

Cc1c(C)c(C)c(-c2c(O)cc(Br)c(Br)c2Br)c(O)c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
AKR1B1 P15121 5/20 0.35
ALOX15 P16050 4/20 0.32
ALOX12 P18054 3/20 0.32
ACLY P53396 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 2/20 0.31
MAPT P10636 2/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065661 0.79 ALOX15 (0.34) AKR1B1ALOX15ALOX12ALDH1A1HPGD
SCHEMBL10363177 0.77 ALDH1A1 (0.34) ALOX15ALOX12ALDH1A1HPGDKDM4E
SCHEMBL31061824 0.73 ALDH1A1 (0.41) CA1CA2CA4CA6ALOX15
SCHEMBL158803 0.73 ALDH1A1 (0.41) CA1CA2CA4CA6ALOX15
SCHEMBL28498022 0.72 ACHE (0.43) CA1CA2CA4CA6AKR1B1
SCHEMBL992964 0.71 SENP1 (0.39)
SCHEMBL9850736 0.69 TRPA1 (0.39) CA1CA2CA6ALOX15ALOX12
SCHEMBL162989 0.68 KDM4E (0.37) ALOX15ALOX12ACLYALDH1A1HPGD
SCHEMBL7754486 0.68 CA1 (0.40) CA1CA2CA4CA6AKR1B1
SCHEMBL5793968 0.68 CYP3A4 (0.43) CA1CA2CA4CA6ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0552278-B1 FLAME RETARDANT EPOXY MOLDING COMPOUND AND PROCESS FOR ENCAPSULATING A DEVICE DEXTER ELECTRONIC MATERIALS DI (US) 1996-07-24 EP disclosed
EP-0259450-B1 PROCESS FOR THE PREPARATION OF TRIBROMOTETRAMETHYLBIPHENOL AND RELATED COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1991-12-27 EP disclosed
EP-0245859-B1 PROCESS FOR THE PREPARATION OF BROMINATED BISPHENOLS THE DOW CHEMICAL COMPANY (US) 1990-10-17 EP disclosed
EP-0259450-A4 PROCESS FOR THE PREPARATION OF TRIBROMOTETRAMETHYLBIPHENOL AND RELATED COMPOUNDS. DOW CHEMICAL CO (US) 1988-06-20 EP disclosed
EP-0259450-A1 PROCESS FOR THE PREPARATION OF TRIBROMOTETRAMETHYLBIPHENOL AND RELATED COMPOUNDS. DOW CHEMICAL CO (US) 1988-03-16 EP disclosed
EP-0245859-A1 Process for the preparation of brominated bisphenols THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
WO-1987005009-A1 PROCESS FOR THE PREPARATION OF TRIBROMOTETRAMETHYLBIPHENOL AND RELATED COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1987-08-27 WO disclosed
US-4654447-A FLAME RETARDENT ADDITIVES, REACTING A 3,3',5,5'-TETRASUBSTITUTED DIPHENOQUINONE AND BROMINE THE DOW CHEMICAL COMPANY (US) 1987-03-31 US disclosed
US-4654447-A FLAME RETARDENT ADDITIVES, REACTING A 3,3',5,5'-TETRASUBSTITUTED DIPHENOQUINONE AND BROMINE THE DOW CHEMICAL COMPANY (US) 1987-03-31 US disclosed
US-4647648-A Polyhydroxyethers from hydroxybiphenyls THE DOW CHEMICAL COMPANY (US) 1987-03-03 US disclosed