Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708575 | 0.86 | LMNA (0.48) | ALDH1A1CYP2C9CYP2C19KMT2AHSD17B10 | |
| SCHEMBL2666743 | 0.83 | PKM (0.41) | MEN1KMT2APKMHTTPOLB | |
| SCHEMBL9072251 | 0.81 | SMN1; SMN2 (0.46) | DHFRALDH1A1GAATSHRKDM4E | |
| SCHEMBL8993717 | 0.76 | ALDH1A1 (0.53) | DHFRALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL2666926 | 0.74 | MAOA (0.44) | ALDH1A1MEN1KMT2APKMTP53 | |
| SCHEMBL13282388 | 0.74 | TSHR (0.53) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL2666928 | 0.74 | HTR2C (0.41) | ALDH1A1MEN1KMT2APKMGAA | |
| SCHEMBL2666963 | 0.73 | POLB (0.50) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL2667069 | 0.71 | DRD2 (0.39) | ALDH1A1GAATSHRKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL10377249 | 0.71 | DHFR (0.63) | DHFRALDH1A1CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061923-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-05-31 | — | — | WO | disclosed |