Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 10/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108781 | 0.92 | F11 (0.38) | F11KLKB1GCKMETAP2 | |
| SCHEMBL9105979 | 0.88 | ALDH1A1 (0.44) | GCKALDH1A1 | |
| SCHEMBL9109081 | 0.88 | ALDH1A1 (0.42) | F11KLKB1GCKMETAP2ALDH1A1 | |
| SCHEMBL9107290 | 0.87 | CUL4A (0.43) | GCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9105493 | 0.87 | PARK7 (0.39) | GCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9109747 | 0.84 | ALDH1A1 (0.46) | GCKALDH1A1 | |
| SCHEMBL9104240 | 0.83 | CHRM5 (0.45) | ALDH1A1 | |
| SCHEMBL9107847 | 0.82 | GCK (0.40) | GCKALDH1A1 | |
| SCHEMBL9108726 | 0.81 | NPSR1 (0.42) | F11KLKB1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL9105799 | 0.81 | GCK (0.36) | GCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142705-A1 | ISATIN AND OXINDOLE COMPOUNDS | KESTER ROBERT FRANCIS (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142705-A1 | ISATIN AND OXINDOLE COMPOUNDS | GPR119, INSR, OAT | F11 2829/4885KLKB1 4398/4885GCK 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.