Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | USP19 | O94966 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109372 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GAAUSP19MEN1KMT2A | |
| SCHEMBL9105979 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGCK | |
| SCHEMBL9107847 | 0.85 | GCK (0.40) | ALDH1A1USP19RENGCK | |
| SCHEMBL9107290 | 0.84 | CUL4A (0.43) | ALDH1A1USP19CES1GCK | |
| SCHEMBL9108781 | 0.84 | F11 (0.38) | RENRAB9AGCK | |
| SCHEMBL9106688 | 0.84 | GCK (0.36) | ALDH1A1GAAUSP19RENGCK | |
| SCHEMBL9105493 | 0.84 | PARK7 (0.39) | ALDH1A1GAAMEN1KMT2AHSD17B10 | |
| SCHEMBL9102207 | 0.84 | F11 (0.40) | ALDH1A1GCK | |
| SCHEMBL9105799 | 0.84 | GCK (0.36) | ALDH1A1GAAUSP19RENGCK | |
| SCHEMBL9107551 | 0.83 | RAB9A (0.36) | ALDH1A1GAAUSP19KMT2AREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142705-A1 | ISATIN AND OXINDOLE COMPOUNDS | KESTER ROBERT FRANCIS (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142705-A1 | ISATIN AND OXINDOLE COMPOUNDS | GPR119, INSR, OAT | ALDH1A1 646/4885GAA 1195/4885USP19 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.