Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL8993919 | 0.96 | SOAT1 (0.32) | CYP3A4TSHRNFKB1NPSR1SOAT1 | |
| SCHEMBL7592817 | 0.86 | SOAT1 (0.39) | SOAT1ALDH1A1 | |
| SCHEMBL7592821 | 0.82 | SOAT1 (0.36) | SOAT1ALDH1A1 | |
| SCHEMBL7835353 | 0.79 | ALDH1A1 (0.40) | CYP3A4TSHRNFKB1NPSR1SOAT1 | |
| SCHEMBL856417 | 0.77 | ALDH1A1 (0.34) | CYP3A4TSHRNFKB1NPSR1SOAT1 | |
| Potassium Ion SCHEMBL9580669 | 0.74 | — | — | |
| SCHEMBL1396971 | 0.69 | CYP3A4 (0.44) | CYP3A4TSHRNFKB1NPSR1ALDH1A1 | |
| SCHEMBL2148474 | 0.69 | ALDH1A1 (0.48) | NPSR1SOAT1ALDH1A1 | |
| SCHEMBL10502342 | 0.69 | CYP1A2 (0.35) | ALDH1A1 | |
| SCHEMBL6028711 | 0.69 | ALDH1A1 (0.42) | SOAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636170-A1 | THIXOTROPIC LIQUID AUTOMATIC DISHWASHING COMPOSITION WITH ENZYME. | PROCTER & GAMBLE (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021299-A1 | THIXOTROPIC LIQUID AUTOMATIC DISHWASHING COMPOSITION WITH ENZYME | THE PROCTER & GAMBLE COMPANY (US) | 1993-10-28 | — | — | WO | disclosed |