Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439628 | 0.86 | NAMPT (0.44) | ALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL23175206 | 0.85 | BACE1 (0.46) | MMP2 | |
| SCHEMBL1404234 | 0.85 | LTA4H (0.42) | LTA4HALDH1A1LMNAKDM4ERXFP1 | |
| SCHEMBL4609875 | 0.84 | LARS1 (0.43) | CYP1A2CYP3A4CYP2D6MAPTPKM | |
| SCHEMBL731316 | 0.79 | METAP2 (0.50) | DHFRLTA4H | |
| SCHEMBL1478261 | 0.77 | LMNA (0.47) | LTA4HALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL11116252 | 0.74 | HDAC8 (0.48) | LTA4HALDH1A1KDM4E | |
| SCHEMBL16061398 | 0.74 | REN (0.44) | P2RY12 | |
| SCHEMBL9115646 | 0.73 | TNIK (0.43) | LTA4HALDH1A1LMNAKDM4ERXFP1 | |
| SCHEMBL6819797 | 0.71 | MAPT (0.50) | LMNARXFP1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995012679-A1 | ANTI-HELMINTH VACCINES | BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (GB) | 1995-05-11 | — | — | WO | disclosed |