Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9084422 | 0.85 | CASP1 (0.36) | ALDH1A1 | |
| SCHEMBL9082309 | 0.84 | LTA4H (0.38) | ALDH1A1PREP | |
| SCHEMBL7448545 | 0.72 | SMN1; SMN2 (0.53) | ALDH1A1PREPSMN1; SMN2 | |
| SCHEMBL2857739 | 0.71 | SMN1; SMN2 (0.58) | SMN1; SMN2 | |
| SCHEMBL17409351 | 0.71 | CYP2C19 (0.40) | DRD2DRD3 | |
| SCHEMBL11217794 | 0.70 | OPRL1 (0.57) | OPRL1DRD2DRD4DRD3 | |
| SCHEMBL9781910 | 0.70 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL9204131 | 0.70 | CTSL (0.36) | ALDH1A1 | |
| SCHEMBL5871698 | 0.70 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2102326 | 0.69 | HTR1A (0.43) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995016682-A1 | CYCLIC AMIDE DERIVATIVES AS NEUROKININ A ANTAGONISTS | ZENECA LIMITED (GB) | 1995-06-22 | — | — | WO | disclosed |