SCHEMBL915494

SCHEMBL915494

FC1(F)C(c2cc(-c3cccs3)sc2-c2cccs2)=C(c2cc(-c3cccs3)sc2-c2cccs2)C(F)(F)C1(F)F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PDK2 Q15119 1/20 0.34
KCNH2 Q12809 1/20 0.33
SLC6A11 P48066 1/20 0.33
LTA4H P09960 2/20 0.33
KDM4E B2RXH2 3/20 0.32
MAPT P10636 3/20 0.32
NPC1 O15118 2/20 0.32
DPP4 P27487 2/20 0.32
MAOB P27338 1/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
GAA P10253 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
GLA P06280 1/20 0.31
CYP2E1 P05181 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16021800 0.96 DPP4 (0.39) MEN1KMT2APDK2KCNH2SLC6A11
SCHEMBL21291337 0.90 PGR (0.33) MEN1KMT2APDK2SLC6A11KDM4E
SCHEMBL14838325 0.89 HSD17B1 (0.38) PDK2KCNH2SLC6A11LTA4HKDM4E
SCHEMBL14838253 0.89 HDAC1 (0.33) MEN1KMT2ALTA4HKDM4EMAPT
SCHEMBL14838258 0.88 ALDH1A1 (0.34) MEN1KMT2ALTA4HKDM4EMAPT
SCHEMBL14838249 0.88 HDAC1 (0.31) LTA4HDPP4HDAC1
SCHEMBL10035948 0.86 LTA4H (0.31) LTA4HDPP4
SCHEMBL14838413 0.86 DPP4 (0.41) MEN1KMT2ALTA4HKDM4EMAPT
SCHEMBL14838370 0.86 DPP4 (0.32) PDK2KCNH2SLC6A11LTA4HKDM4E
SCHEMBL14838420 0.86 DPP4 (0.35) MEN1KMT2ALTA4HKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124524-B2 Diarylethene compounds and uses thereof SOLUTIA CANADA INC. (US) 2021-09-21 US disclosed
US-11079617-B2 Optical filter comprising a variable transmittance layer Solatia Canada Inc. (CA) 2021-08-03 US disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 US disclosed
US-10556912-B2 Diarylethene compounds and uses thereof SWITCH MATERIALS, INC. (CA) 2020-02-11 US disclosed
US-20200033687-A1 VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF SWITCH MAT INC (CA) 2020-01-30 US disclosed
US-20190346699-A1 OPTICAL FILTER COMPRISING A VARIABLE TRANSMITTANCE LAYER SOLUTIA CANADA INC. (CA) 2019-11-14 US disclosed
US-10401654-B2 Optical filter comprising a variable transmittance layer SWITCH MATERIALS INC. (CA) 2019-09-03 US disclosed
US-20190256526-A1 DIARYLETHENE COMPOUNDS AND USES THEREOF SWITCH MATERIALS, INC. (CA) 2019-08-22 US disclosed
US-10254616-B2 Variable transmittance optical filter with substantially co-planar electrode system SWITCH MATERIALS, INC. (CA) 2019-04-09 US disclosed
US-20180224677-A1 OPTICAL FILTER COMPRISING A VARIABLE TRANSMITTANCE LAYER SOLUTIA CANADA INC. (CA) 2018-08-09 US disclosed
EP-1955328-A1 OPTICAL ARTICLE HAVING ANTI-THEFT FEATURE AND A SYSTEM AND METHOD FOR INHIBITING THEFT OF SAME General Electric Company (US) 2008-08-13 EP disclosed
EP-1955327-A1 OPTICAL ARTICLE HAVING ANTI-THEFT FEATURE AND A SYSTEM AND METHOD FOR INHIBITING THEFT OF SAME General Electric Company (US) 2008-08-13 EP disclosed
WO-2007061776-A1 OPTICAL ARTICLE HAVING ANTI-THEFT FEATURE AND A SYSTEM AND METHOD FOR INHIBITING THEFT OF SAME GENERAL ELECTRIC COMPANY (US) 2007-05-31 WO disclosed
WO-2007061974-A1 OPTICAL ARTICLE HAVING ANTI-THEFT FEATURE AND A SYSTEM AND METHOD FOR INHIBITING THEFT OF SAME GENERAL ELECTRIC COMPANY (US) 2007-05-31 WO disclosed
US-20070115762-A1 Optical article having anti-theft feature and a system and method for inhibiting theft of same GENERAL ELECTRIC COMPANY 2007-05-24 US disclosed
WO-2007059288-A1 OPTICAL DATA CARRIER HAVING ANTI-THEFT FEATURE BY ACTIVATING / DE-ACTIVATING AN ELECTRO- CHROMIC STRUCTURE GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO disclosed
US-20070116988-A1 Optical article having anti-theft feature and a system and method for inhibiting theft of same GENERAL ELECTRIC COMPANY 2007-05-24 US disclosed
US-20070114365-A1 Optical article having anti-theft feature and a system and method for inhibiting theft of same NBCUNIVERSAL MEDIA, LLC 2007-05-24 US disclosed
US-20060240197-A1 Photochromic and electrochromic compounds and methods of synthesizing and using same SOLUTIA CANADA INC. (CA) 2006-10-26 US disclosed
WO-2004015024-A1 PHOTOCHROMIC AND ELECTROCHROMIC COMPOUNDS AND METHODS OF SYNTHESIZING AND USING SAME SIMON FRASER UNIVERSITY (CA) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190256526-A1 DIARYLETHENE COMPOUNDS AND USES THEREOF KCNH2, KCNH3, SCN2B MEN1 4315/4885KMT2A 1512/4885PDK2 4186/4885
US-10556912-B2 Diarylethene compounds and uses thereof KCNH2, KCNH3, SCN2B MEN1 4315/4885KMT2A 1512/4885PDK2 4186/4885
US-10254616-B2 Variable transmittance optical filter with substantially co-planar electrode system HCN2, HCN4, HCN1 MEN1 1368/4885KMT2A 2600/4885PDK2 1511/4885
US-20060240197-A1 Photochromic and electrochromic compounds and methods of synthesizing and using same TET1, HMBS, MECP2 MEN1 1812/4885KMT2A 335/4885PDK2 2102/4885
US-11124524-B2 Diarylethene compounds and uses thereof KCNH2, KCNH3, SCN2B MEN1 4315/4885KMT2A 1512/4885PDK2 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.