Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 10/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175683 | 0.84 | RAB9A (0.34) | ALDH1A1LMNAAGTR1MAOBNPC1 | |
| SCHEMBL9174736 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAOBNPC1TSHR | |
| SCHEMBL8980907 | 0.79 | MAOB (0.39) | ALDH1A1MAOBNPC1HPGD | |
| SCHEMBL9174109 | 0.79 | MAOB (0.39) | MAOBNPC1TSHR | |
| SCHEMBL9167754 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNAAGTR1MAOBACHE | |
| SCHEMBL6436979 | 0.68 | ALDH1A1 (0.36) | ALDH1A1LMNAAGTR1MAOBACHE | |
| SCHEMBL9170026 | 0.67 | ROCK2 (0.40) | ALDH1A1MAOBACHENPC1 | |
| SCHEMBL9303669 | 0.66 | CA2 (0.35) | ALDH1A1LMNAMAOBNPC1TSHR | |
| SCHEMBL9190169 | 0.64 | LMNA (0.36) | ALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL8658972 | 0.64 | SMN1; SMN2 (0.39) | ALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490183-B1 | Benzoxazinone and benzothiazinone derivatives endowed with cardiovascular activity | ITALFARMACO SPA (IT) | 1995-04-19 | — | — | EP | disclosed |
| US-5189034-A | Vasodilating, antianginal agents | ITALFARMACO S.P.A. (IT) | 1993-02-23 | — | — | US | disclosed |
| EP-0490183-A1 | Benzoxazinone and benzothiazinone derivatives endowed with cardiovascular activity | ITALFARMACO S.p.A. (IT) | 1992-06-17 | — | — | EP | disclosed |