Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | EED | O75530 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23507392 | 0.85 | FAAH (0.56) | FAAHLMNAEEDMEN1ALDH1A1 | |
| SCHEMBL13448606 | 0.81 | FAAH (0.56) | FAAHLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL918275 | 0.81 | FAAH (0.53) | FAAHLMNAEEDMEN1ALDH1A1 | |
| SCHEMBL14375244 | 0.79 | ACHE (0.55) | FAAHLMNAEEDMEN1ALDH1A1 | |
| SCHEMBL10101037 | 0.78 | FAAH (0.53) | FAAHLMNAEEDMEN1ALDH1A1 | |
| SCHEMBL211923 | 0.77 | FAAH (0.72) | FAAHLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL6266386 | 0.74 | ADRB1 (0.77) | LMNAALDH1A1DRD2DRD1SIGMAR1 | |
| SCHEMBL14197726 | 0.74 | LMNA (0.55) | FAAHLMNAEEDMEN1ALDH1A1 | |
| SCHEMBL23507557 | 0.74 | LMNA (0.55) | FAAHLMNAEEDMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL12478620 | 0.73 | ADRB1 (0.74) | LMNAALDH1A1DRD2DRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654834-B2 | Non-systemic TGR5 agonists | Venenum Biodesign, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190330191-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | Venenum Biodesign, LLC (US) | 2019-10-31 | — | — | US | disclosed |
| EP-1951842-B1 | USE OF RYLENE DERIVATIVES AS PHOTOSENSITIZERS IN SOLAR CELLS | BASF SE (DE) | 2016-07-27 | — | — | EP | disclosed |
| US-8981131-B2 | Tricyclic compounds for the treatment of inflammatory disorders | Piramal Enterprises Limited (IN) | 2015-03-17 | — | — | US | disclosed |
| US-8501046-B2 | Use of rylene derivatives as photosensitizers in solar cells | BASF SE (DE) | 2013-08-06 | — | — | US | disclosed |
| US-20120283432-A1 | USE OF RYLENE DERIVATIVES AS PHOTOSENSITIZERS IN SOLAR CELLS | MAX-PLANCK-GESEL. ZUR FOERDERUNG DER WISSEN. E.V. (DE) | 2012-11-08 | — | — | US | disclosed |
| US-8231809-B2 | Solid p-semiconductors may also be used in the inventive dye-sensitized solar cells without increasing the cell resistance, since the rylene derivatives absorb strongly and therefore require only thin n-semiconductor layers | BASF AKTIENGESELLSCHAFT (DE) | 2012-07-31 | — | — | US | disclosed |
| US-8083971-B2 | Use of rylene derivatives as active components in solar cells and photodetectors | BASF SE (DE) | 2011-12-27 | — | — | US | disclosed |
| US-8071775-B2 | photovoltaics; emitters in chemiluminescence applications; field-effect transistors and electrophotography; N,N'-Bis(2,6-diisopropylphenyl)-1,7- and -1,6-bis(2,6-diisopropylphenoxy)-perylene-3,4:9,10-tetracarboximide | BASF AKTIENGESELLSCHAFT (DE) | 2011-12-06 | — | — | US | disclosed |
| EP-1904497-B1 | SUBSTITUTED RYLENE DERIVATIVES | BASF SE (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-20110009396-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | Piramal Enterprises Limited (IN) | 2011-01-13 | — | — | US | disclosed |
| US-20100207072-A1 | USE OF RYLENE DERIVATIVES AS ACTIVE COMPONENTS IN SOLAR CELLS AND PHOTODETECTORS | BASF SE (DE) | 2010-08-19 | — | — | US | disclosed |
| US-20100011656-A1 | USE OF RYLENES AS MARKERS FOR LIQUIDS | BASF SE (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20090124732-A1 | Rylene Tetracarboxylic Acid Diimides Substituted By Cyclic Amino Groups | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-14 | — | — | US | disclosed |
| WO-2009016565-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2009-02-05 | — | — | WO | disclosed |
| US-20080269482-A1 | Use of Rylene Derivatives as Photosensitizers in Solar Cells | BASF SE (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080167467-A1 | Substituted Rylene Derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167467-A1 | Substituted Rylene Derivatives | NR3C2, NR2C2, NR2E3 | FAAH 4397/4885LMNA 4546/4885EED 1671/4885 |
| US-20090124732-A1 | Rylene Tetracarboxylic Acid Diimides Substituted By Cyclic Amino Groups | NR1I3, NR1I2, NR1H3 | FAAH 1530/4885LMNA 2865/4885EED 2826/4885 |
| US-20190330191-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | GPR119, FFAR1, FFAR3 | FAAH 447/4885LMNA 4460/4885EED 4842/4885 |
| US-20120283432-A1 | USE OF RYLENE DERIVATIVES AS PHOTOSENSITIZERS IN SOLAR CELLS | NR2E3, NR2E1, NR1D2 | FAAH 4618/4885LMNA 2818/4885EED 361/4885 |
| US-10654834-B2 | Non-systemic TGR5 agonists | GPR119, SSTR5, FFAR3 | FAAH 502/4885LMNA 4382/4885EED 4833/4885 |
| US-20100207072-A1 | USE OF RYLENE DERIVATIVES AS ACTIVE COMPONENTS IN SOLAR CELLS AND PHOTODETECTORS | NR2E3, NR1H2, NR1H3 | FAAH 3811/4885LMNA 2162/4885EED 2342/4885 |
| US-20110009396-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | IL1R1, IL1B, IL1A | FAAH 2031/4885LMNA 1971/4885EED 4813/4885 |
| US-20100011656-A1 | USE OF RYLENES AS MARKERS FOR LIQUIDS | RPL22, PROX1, RPL29 | FAAH 4143/4885LMNA 3892/4885EED 1964/4885 |
| US-20080269482-A1 | Use of Rylene Derivatives as Photosensitizers in Solar Cells | NR2E3, NR2E1, NR1D2 | FAAH 4611/4885LMNA 2900/4885EED 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.