Sugi Predict

Sugi Predict / Compounds / SCHEMBL917833

SCHEMBL917833

SCHEMBL917833

CN1C(=O)c2ccc(N)cc2C1=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.59
▸ HSD17B10 Q99714 4/20 0.59
▸ CASP1 P29466 3/20 0.59
▸ NPC1 O15118 3/20 0.59
▸ RAB9A P51151 3/20 0.59
▸ TSHR P16473 2/20 0.59
▸ CASP7 P55210 1/20 0.59
▸ ANPEP P15144 2/20 0.56
▸ DPP4 P27487 1/20 0.56
▸ NR1H2 P55055 1/20 0.56
▸ NR1H3 Q13133 1/20 0.56
▸ MEN1 O00255 4/20 0.54
▸ KMT2A Q03164 4/20 0.54
▸ MAPK1 P28482 2/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ MAPT P10636 2/20 0.52
▸ L3MBTL1 Q9Y468 2/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ GAA P10253 1/20 0.51
▸ APP P05067 6/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29833030 1.00 ALDH1A1 (0.59) ALDH1A1HSD17B10CASP1NPC1RAB9A
SCHEMBL24167716 0.80 ALDH1A1 (0.56) ALDH1A1HSD17B10CASP1NPC1RAB9A
SCHEMBL617579 0.80 ALDH1A1 (0.51) ALDH1A1HSD17B10NPC1RAB9ATSHR
SCHEMBL8005568 0.79 CASP1 (0.60) ALDH1A1HSD17B10CASP1NPC1RAB9A
SCHEMBL2901880 0.78 ALDH1A1 (0.55) ALDH1A1HSD17B10CASP1NPC1RAB9A
SCHEMBL42876 0.78 ALDH1A1 (0.55) ALDH1A1HSD17B10CASP1NPC1RAB9A
SCHEMBL6207310 0.78 POLB (0.57) ALDH1A1HSD17B10CASP1NPC1RAB9A
SCHEMBL30070294 0.78 POLB (0.57) ALDH1A1HSD17B10CASP1NPC1RAB9A
SCHEMBL1950000 0.78 ANPEP (0.55) ALDH1A1HSD17B10CASP1NPC1RAB9A
SCHEMBL13604050 0.78 ALDH1A1 (0.54) ALDH1A1HSD17B10CASP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798138-A N-methyl-4-amino phthalimide and preparation method thereof 浙江闰土股份有限公司 2025-04-11 — — CN claimed
CN-118185101-A Gas polarity sensing film and preparation method and application thereof 中国科学院大连化学物理研究所 2024-06-14 — — CN claimed
CN-109535044-B Diazotization method of aromatic primary amine 金华双宏化工有限公司 2021-06-15 — — CN claimed
CN-107365492-A A kind of automobile plastic shock absorber part preparation method 无为县大江橡塑制品有限公司 2017-11-21 — — CN claimed
CN-105482258-A Cable insulation layer material with excellent mechanical property and preparing method of cable insulation layer material ANHUI RUIKAN SCIENCE CABLE CO LTD 2016-04-13 — — CN claimed
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORPORATION (US) 2010-10-07 — — US claimed
EP-1819341-A2 IL-12 MODULATORY COMPOUNDS Synta Pharmaceuticals Corporation (US) 2007-08-22 — — EP claimed
US-20060223996-A1 IL-12 modulatory compounds SYNTA PHARMACEUTICALS CORP. (US) 2006-10-05 — — US claimed
WO-2006053227-A2 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORP. (US) 2006-05-18 — — WO claimed
EP-0431452-B1 Method for the optical distinction of dental materials and material used in this method IVOCLAR AG (LI) 1994-10-05 — — EP claimed
US-5102461-A PROCESS FOR THE OPTICAL DISTINCTION OF A DENTAL MATERIAL AND DENTAL MATERIAL FOR SAID PROCESS IVOCLAR AG (DE) 1992-04-07 — — US claimed
EP-0431452-A2 Method for the optical distinction of dental materials and material used in this method IVOCLAR AG (LI) 1991-06-12 — — EP claimed
US-12497645-B2 Self-immolative probes for enzyme activity detection ENZO LIFE SCIENCES, INC. (US) 2025-12-16 — — US disclosed
CN-119798138-A N-methyl-4-amino phthalimide and preparation method thereof 浙江闰土股份有限公司 2025-04-11 — — CN disclosed
CN-119798138-A N-methyl-4-amino phthalimide and preparation method thereof 浙江闰土股份有限公司 2025-04-11 — — CN disclosed
CN-119798138-A N-methyl-4-amino phthalimide and preparation method thereof 浙江闰土股份有限公司 2025-04-11 — — CN disclosed
US-4355165-A CHEMILUMIMESCENCE, IMMUNOASSAY MILES LABORATORIES, INC. (US) 1982-10-19 — — US disclosed
WO-1982000641-A1 PEPTIDE SUBSTRATES FOR DETERMINATION OF PROTEASE ACTIVITY KABIVITRUM AB (SE) 1982-03-04 — — WO disclosed
EP-0046742-A1 Peptide substrates for determination of protease activity KabiVitrum AB (SE) 1982-03-03 — — EP disclosed
US-4261893-A INTERMEDIATES IN SYNTHESIS OF CHEMILUMINESCENT-LABELED CONJUGATES USED IN IMMUNOASSAYS MILES LABORATORIES, INC. (US) 1981-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223996-A1 IL-12 modulatory compounds IL2, IL4, IFNG ALDH1A1 1381/4885HSD17B10 1025/4885CASP1 231/4885
US-12497645-B2 Self-immolative probes for enzyme activity detection SORD, SI, IMMT ALDH1A1 371/4885HSD17B10 665/4885CASP1 563/4885
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS IL2, IL4, IFNG ALDH1A1 1381/4885HSD17B10 1025/4885CASP1 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.