Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | HPN | P05981 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184400 | 0.87 | MT-CO2 (0.42) | MEN1KMT2AMT-CO2ALOX5LMNA | |
| SCHEMBL9186217 | 0.74 | TP53 (0.42) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9186146 | 0.73 | FAAH (0.39) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9181777 | 0.72 | HPGD (0.42) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL9188526 | 0.71 | MCHR1 (0.40) | L3MBTL1 | |
| SCHEMBL9181710 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9188796 | 0.69 | CNR1 (0.43) | KMT2A | |
| SCHEMBL9182339 | 0.68 | TRPA1 (0.42) | LMNATRPA1 | |
| SCHEMBL9181121 | 0.68 | CRHR1 (0.31) | KMT2APOLB | |
| SCHEMBL9187128 | 0.67 | ALDH1A1 (0.42) | MT-CO2ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455300-B1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INT RES (NL) | 1995-06-28 | — | — | EP | disclosed |
| US-5164396-A | Control of aphids | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-17 | — | — | US | disclosed |
| EP-0455300-A1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-11-06 | — | — | EP | disclosed |