SCHEMBL919571

SCHEMBL919571

Clc1cccc(Oc2c[c]ccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.44
SLC6A4 P31645 3/20 0.43
KCNH2 Q12809 2/20 0.43
HTR2A P28223 1/20 0.43
RHEB Q15382 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
SLC6A2 P23975 2/20 0.40
SLC6A3 Q01959 2/20 0.40
WDR5 P61964 1/20 0.38
LMNA P02545 2/20 0.37
HTR1A P08908 1/20 0.37
CYP19A1 P11511 1/20 0.37
SCN5A Q14524 1/20 0.37
SCN9A Q15858 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1282838 0.87 TERT (0.39) ARSLC6A4KCNH2HTR2ARHEB
SCHEMBL6206121 0.82 RHEB (0.52) ARSLC6A4KCNH2HTR2ARHEB
SCHEMBL8155454 0.82 LTA4H (0.43) SMN1; SMN2MAPT
SCHEMBL29924283 0.82 RHEB (0.52) ARSLC6A4KCNH2HTR2ARHEB
SCHEMBL511009 0.81 MAOA (0.47) ARSLC6A4HTR2ACYP1A2CYP2C9
SCHEMBL693645 0.81 AR (0.46) ARSLC6A4KCNH2HTR2ARHEB
SCHEMBL9261806 0.81 MAOB (0.48) SMN1; SMN2MAPT
SCHEMBL1282538 0.80 KMO (0.49) SLC6A4KCNH2HTR2ASLC6A2SLC6A3
SCHEMBL9687090 0.80 SMN1; SMN2 (0.37) CYP1A2CYP2C9CYP2C19LMNAHTT
SCHEMBL27903184 0.80 SOS1 (0.48) ARSLC6A4KCNH2HTR2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103119030-A Matrix metalloproteinase inhibitors RANBAXY LAB LTD 2013-05-22 CN claimed
US-20110160056-A1 Triazole compounds, the use thereof and preparations containing these compounds BASF SE (DE) 2011-06-30 US claimed
EP-2328878-A1 TRIAZOLE COMPOUNDS, THE USE THEREOF AND PREPARATIONS CONTAINING THESE COMPOUNDS BASF SE (DE) 2011-06-08 EP claimed
WO-2010029000-A1 TRIAZOLE COMPOUNDS, THE USE THEREOF AND PREPARATIONS CONTAINING THESE COMPOUNDS BASF SE (DE) 2010-03-18 WO claimed
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-10077254-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-09-18 US disclosed
EP-3059233-B1 TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME SUMITOMO CHEMICAL CO (JP) 2017-12-20 EP disclosed
EP-2841433-B1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL CO (JP) 2017-06-21 EP disclosed
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed
US-20160272622-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-22 US disclosed
EP-3059233-A1 TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME Sumitomo Chemical Company, Limited (JP) 2016-08-24 EP disclosed
US-9380782-B2 Tetrazolinone compounds and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
US-4864027-A INSECTICIDES, NEMATOCIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0288810-A1 Heterocyclic neophane analogs, processes for their preparation and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-02 EP disclosed
CN-88102112-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides 1988-10-26 CN disclosed
US-4775664-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-04 US disclosed
CN-87102981-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1988-03-02 CN disclosed
CN-86107292-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1987-07-29 CN disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10077254-B2 Tetrazolinone compound and use thereof MT-CO1, UQCRB, MT-CO2 AR 2729/4885SLC6A4 4588/4885KCNH2 615/4885
US-20110160056-A1 Triazole compounds, the use thereof and preparations containing these compounds CYP11B2, CYP3A43, CYP3A5 AR 3643/4885SLC6A4 2344/4885KCNH2 2680/4885
US-20160272622-A1 TETRAZOLINONE COMPOUND AND USE THEREOF MT-CO1, UQCRB, MT-CO2 AR 2729/4885SLC6A4 4588/4885KCNH2 615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.