SCHEMBL920004

SCHEMBL920004

COCc1ccc(C(=O)NCc2ccc(Oc3ccc(CC(C)(C)C)cc3)cc2)c(N)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.39
PPARA Q07869 2/20 0.39
KMT2A Q03164 2/20 0.38
EPHX2 P34913 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
DHFR P00374 1/20 0.38
MAPK14 Q16539 2/20 0.38
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
MMP13 P45452 2/20 0.37
CHRM4 P08173 1/20 0.37
FLT1 P17948 1/20 0.37
LRRK2 Q5S007 1/20 0.37
MMP2 P08253 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921382 0.92 PPARG (0.43) PPARAMAPK14ALDH1A1HPGDMMP13
SCHEMBL922841 0.89 EGLN1 (0.49) EGLN1KMT2AL3MBTL1ALDH1A1HPGD
SCHEMBL922079 0.89 MAPK14 (0.50) EGLN1KMT2AMEN1MAPK14ALDH1A1
SCHEMBL920018 0.89 TP53 (0.41) EGLN1PPARAKMT2ALIPGMAPK14
SCHEMBL919997 0.89 MAPK14 (0.50) EGLN1PPARAEPHX2NPC1L3MBTL1
SCHEMBL920784 0.88 RIPK1 (0.41) EGLN1KMT2AMEN1L3MBTL1MAPK14
SCHEMBL920779 0.88 LIPG (0.51) PPARAL3MBTL1LIPGMAPK14CYP3A4
SCHEMBL920880 0.88 EGLN1 (0.41) EGLN1KMT2ALIPGMAPK14ALDH1A1
SCHEMBL921652 0.88 AKR1B1 (0.41) EGLN1KMT2ALIPGMAPK14ALDH1A1
SCHEMBL920636 0.88 CYP3A4 (0.48) EGLN1KMT2AL3MBTL1MAPK14ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 EGLN1 430/4885PPARA 494/4885KMT2A 2469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.