SCHEMBL920294

SCHEMBL920294

Fc1ccc(Cc2cc[c]s2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
P2RX7 Q99572 1/20 0.37
IDO1 P14902 3/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
SMN1; SMN2 Q16637 6/20 0.36
TP53 P04637 5/20 0.36
DAO P14920 1/20 0.36
TAAR1 Q96RJ0 2/20 0.35
AGXT P21549 2/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX5 P09917 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919851 0.80 ALDH1A1 (0.47) ALDH1A1IDO1SMN1; SMN2TP53DAO
SCHEMBL919866 0.78 P2RX7 (0.43) MAPTALDH1A1HPGDLMNAP2RX7
SCHEMBL921911 0.76 LTA4H (0.48) MAPTALDH1A1HPGDLMNAIDO1
SCHEMBL1468357 0.69 IDO1 (0.58) ALDH1A1LMNAIDO1LOXL2DAO
SCHEMBL16561361 0.69 IDO1 (0.58) ALDH1A1LMNAIDO1LOXL2DAO
Hydrochloric Acid SCHEMBL7941845 0.67 IDO1 (0.55) ALDH1A1LMNAIDO1LOXL2DAO
SCHEMBL3032997 0.67 IDO1 (0.44) MAPTALDH1A1HPGDLMNAGAA
SCHEMBL10492334 0.67 HRH4 (0.47)
SCHEMBL3236567 0.65 HPGD (0.53) HPGDLMNASMN1; SMN2TP53TAAR1
SCHEMBL1631743 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
WO-2008126684-A2 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX MAPT 388/4885ALDH1A1 3801/4885HPGD 1430/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPT 695/4885ALDH1A1 2743/4885HPGD 1273/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 MAPT 1422/4885ALDH1A1 4326/4885HPGD 1474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.