SCHEMBL920378

SCHEMBL920378

Cc1ccc(Cc2cc[c]o2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
ALDH1A1 P00352 3/20 0.37
HTT P42858 1/20 0.37
GAA P10253 1/20 0.36
ALOX12 P18054 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
SRD5A2 P31213 1/20 0.35
AGXT P21549 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
ACHE P22303 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
DAO P14920 1/20 0.33
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920278 0.83 IDO1 (0.38) IDO1ALDH1A1ALOX12KMT2ACYP2A6
SCHEMBL919691 0.82 IDO1 (0.37) IDO1ALDH1A1GAAKMT2ATAAR1
SCHEMBL920282 0.81 LTA4H (0.48) IDO1ALDH1A1TAAR1AGXTLMNA
SCHEMBL8453468 0.78 NQO1 (0.47) ALDH1A1GAALMNAHPGDTDP1
SCHEMBL1149394 0.71 IDO1 (0.58) IDO1ALDH1A1HTTKMT2ACYP1A2
SCHEMBL11410252 0.71 IDO1 (0.58) IDO1ALDH1A1HTTKMT2ACYP1A2
SCHEMBL920155 0.69 PNMT (0.46) IDO1TAAR1AGXTDAO
SCHEMBL3533774 0.69 IDO1 (0.44) IDO1ALDH1A1HTTKMT2ACYP1A2
SCHEMBL10492257 0.68 HRH4 (0.44) CYP1A2CYP2A6TDP1
SCHEMBL920263 0.68 TAAR1 (0.42) IDO1ALDH1A1TAAR1AGXTDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
WO-2008126684-A2 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX IDO1 111/4885ALDH1A1 3801/4885HTT 218/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 IDO1 675/4885ALDH1A1 2743/4885HTT 2561/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 IDO1 236/4885ALDH1A1 4326/4885HTT 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.