SCHEMBL921908

SCHEMBL921908

Cc1cccc(Oc2cc[c]s2)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
GAA P10253 1/20 0.47
ACHE P22303 2/20 0.46
HTT P42858 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.40
AR P10275 3/20 0.38
LYN P07948 1/20 0.38
MRGPRX1 Q96LB2 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
PTGS2 P35354 2/20 0.36
PTGS1 P23219 1/20 0.36
MAPT P10636 1/20 0.36
PPARG P37231 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921337 0.83 SMN1; SMN2 (0.46) ALDH1A1ACHEL3MBTL1LMNAMEN1
SCHEMBL919521 0.79 MMP2 (0.39) ALDH1A1MRGPRX1PTGS2PTGS1MAPT
SCHEMBL919822 0.79 RHEB (0.39) HTTLMNAARPTGS2PTGS1
SCHEMBL920196 0.78 TEAD4 (0.42) ALDH1A1GAAACHEHTTL3MBTL1
SCHEMBL921166 0.77 LTA4H (0.46) HTTLMNAKMT2APTGS2MAPT
SCHEMBL29746015 0.74 ALDH1A1 (0.72) ALDH1A1GAAACHEHTTL3MBTL1
SCHEMBL29398372 0.74 ALDH1A1 (0.72) ALDH1A1GAAACHEHTTL3MBTL1
SCHEMBL456868 0.74 ALDH1A1 (0.72) ALDH1A1GAAACHEHTTL3MBTL1
SCHEMBL2752862 0.73 ALDH1A1 (0.42) ALDH1A1PTGS2
SCHEMBL29377828 0.72 ALDH1A1 (0.69) ALDH1A1GAAACHEHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
WO-2008126684-A2 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX ALDH1A1 3801/4885GAA 920/4885ACHE 1974/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ALDH1A1 2743/4885GAA 3332/4885ACHE 3081/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 ALDH1A1 4326/4885GAA 2649/4885ACHE 4121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.