Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686717 | 1.00 | HTR2A (0.43) | HTR2AHTR2CHTR2BCYP19A1PGR | |
| SCHEMBL23782912 | 0.80 | PGR (0.41) | PGRDRD1DRD2DRD4DRD5 | |
| SCHEMBL29284908 | 0.77 | ALDH1A1 (0.41) | CYP19A1 | |
| SCHEMBL30951195 | 0.77 | ALDH1A1 (0.41) | CYP19A1 | |
| SCHEMBL10650813 | 0.76 | HTR2A (0.44) | HTR2AHTR2CHTR2BCYP19A1CHRNB2 | |
| SCHEMBL1693312 | 0.75 | MAP3K14 (0.51) | HTR2AHTR2CHTR2BPGRPYGL | |
| SCHEMBL29959450 | 0.75 | MAP3K14 (0.51) | HTR2AHTR2CHTR2BPGRPYGL | |
| SCHEMBL15909359 | 0.75 | MAP3K14 (0.51) | HTR2AHTR2CHTR2BPGRPYGL | |
| SCHEMBL1154693 | 0.75 | MAP3K14 (0.47) | HTR2AHTR2CHTR2BPYGLMAP3K14 | |
| SCHEMBL1155475 | 0.75 | MAP3K14 (0.47) | HTR2AHTR2CHTR2BPYGLMAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957041-B | Fluorescent probe for detecting viscosity of industrial lubricating oil and preparation method and application thereof | 华南理工大学 | 2023-03-21 | — | — | CN | claimed |
| CN-114957041-A | Fluorescent probe for detecting viscosity of industrial lubricating oil and preparation method and application thereof | 华南理工大学 | 2022-08-30 | — | — | CN | claimed |
| US-12145929-B2 | Piperidine derivative and pharmaceutical composition for inhibiting autotaxin comprising same | NEXTGEN BIOSCIENCE CO., LTD. (KR) | 2024-11-19 | — | — | US | disclosed |
| US-20240279216-A1 | NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING SAME | NEXTGEN BIOSCIENCE CO., LTD. (KR) | 2024-08-22 | — | — | US | disclosed |
| EP-4353720-A1 | NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2024-04-17 | — | — | EP | disclosed |
| CN-117396471-A | Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same | 株式会社次代生物科学 | 2024-01-12 | — | — | CN | disclosed |
| US-20230381132-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
| US-20230381132-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
| US-20230381132-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
| EP-4237402-A1 | NOVEL COMPOUNDS | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | disclosed |
| WO-2023055178-A1 | NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2023-04-06 | — | — | WO | disclosed |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-07-12 | — | — | US | disclosed |
| WO-2022090714-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022090714-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2021-06-10 | — | — | US | disclosed |
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |
| US-5436244-A | Antiarrhythmia agents | ROUSSEL UCLAF (FR) | 1995-07-25 | — | — | US | disclosed |
| US-5348971-A | Indanes useful as analgesics | ROUSSEL UCLAF (FR) | 1994-09-20 | — | — | US | disclosed |
| EP-0374054-B1 | INDANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES OBTAINED, THEIR USE AS MEDICINES, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-10-06 | — | — | EP | disclosed |
| EP-0374054-A1 | Indane derivatives, process for their preparation and intermediates obtained, their use as medicines, and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1990-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279216-A1 | NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING SAME | ENPP2, UACA, ITCH | HTR2A 4150/4885HTR2C 4783/4885HTR2B 4649/4885 |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | XDH, PNPO, AGXT | HTR2A 4542/4885HTR2C 4184/4885HTR2B 3960/4885 |
| US-20230381132-A1 | NOVEL COMPOUNDS | CNKSR1, RORC, RCOR3 | HTR2A 4466/4885HTR2C 4163/4885HTR2B 4370/4885 |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | HTR2A 4542/4885HTR2C 4184/4885HTR2B 3960/4885 |
| US-12145929-B2 | Piperidine derivative and pharmaceutical composition for inhibiting autotaxin comprising same | ENPP2, UACA, ACAT2 | HTR2A 4274/4885HTR2C 4808/4885HTR2B 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.