Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 13/20 | 0.46 |
| ▸ | TMPRSS15 | P98073 | 13/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252732 | 0.92 | HDAC1 (0.46) | PRSS1TMPRSS15CA2HDAC1HDAC8 | |
| SCHEMBL9250758 | 0.92 | HDAC6 (0.52) | PRSS1TMPRSS15HDAC1HDAC8HDAC6 | |
| SCHEMBL9251560 | 0.88 | ITGB3 (0.47) | PRSS1TMPRSS15HDAC1HDAC8HDAC6 | |
| SCHEMBL9248512 | 0.86 | HDAC1 (0.56) | PRSS1TMPRSS15CA2HDAC1HDAC8 | |
| SCHEMBL9251384 | 0.83 | HDAC1 (0.49) | PRSS1TMPRSS15HDAC1HDAC8HDAC6 | |
| SCHEMBL9255461 | 0.78 | HDAC6 (0.42) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL6165313 | 0.76 | F2 (0.58) | HDAC1HDAC8HDAC6ITGB3ITGA2B | |
| SCHEMBL9255606 | 0.75 | MMP1 (0.39) | ITGB3ITGA2B | |
| SCHEMBL9249572 | 0.73 | ITGB3 (0.56) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL9249490 | 0.73 | HDAC1 (0.56) | PRSS1HDAC1HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |