Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255606 | 0.90 | MMP1 (0.39) | CTSSCTSKCTSLITGB3ITGA2B | |
| SCHEMBL9246050 | 0.87 | HDAC6 (0.40) | MAPTHDAC6ITGB3ITGA2BTMPRSS15 | |
| SCHEMBL9252266 | 0.85 | ACE (0.38) | HDAC6ITGB3ITGA2BTMPRSS15 | |
| SCHEMBL9252204 | 0.85 | LNPEP (0.40) | HDAC6 | |
| SCHEMBL9253897 | 0.85 | LNPEP (0.38) | CTSKHDAC6KMT2AITGB3ITGA2B | |
| SCHEMBL9252697 | 0.84 | HDAC6 (0.42) | ENPP2TP53MAPTCTSSCTSK | |
| SCHEMBL9251560 | 0.79 | ITGB3 (0.47) | ENPP2TP53CTSSHDAC6CTSL | |
| SCHEMBL9255461 | 0.74 | HDAC6 (0.42) | CTSSCTSKHDAC6CTSL | |
| SCHEMBL9252259 | 0.73 | EHMT2 (0.43) | ENPP2TP53MAPTITGB3ITGA2B | |
| SCHEMBL8408125 | 0.71 | CTSL (0.41) | MAPTCTSSCTSKCTSLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |