Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538964 | 0.82 | HTR1A (0.48) | ALDH1A1HTR1ACYP1A2HTR1DHTR1B | |
| SCHEMBL9256337 | 0.81 | HTR7 (0.70) | SLC6A4ALDH1A1HTR1ANPC1RAB9A | |
| SCHEMBL9262780 | 0.81 | MPO (0.62) | SLC6A4HTR7 | |
| SCHEMBL9264998 | 0.80 | HTR7 (0.72) | SLC6A4ALDH1A1HTR1AHTR7MEN1 | |
| SCHEMBL9263244 | 0.77 | GPR84 (0.64) | HRH3ALDH1A1HTR1ANPC1RAB9A | |
| [1,4']Bipiperidinyl SCHEMBL9289448 | 0.76 | HTR7 (0.48) | SLC6A4ALDH1A1HTR1AHTR7MEN1 | |
| Pyrrole SCHEMBL9258023 | 0.76 | HTR7 (0.62) | HTR1ANPC1RAB9AHTR7MEN1 | |
| SCHEMBL9289454 | 0.76 | ADRA2A (0.40) | ALDH1A1HTR1AHTR7MEN1CYP1A2 | |
| SCHEMBL11371837 | 0.75 | HTR1A (0.62) | HRH3HTR1AHTR7MEN1CYP1A2 | |
| SCHEMBL24100580 | 0.75 | HPGD (0.49) | ALDH1A1NPC1RAB9ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |