Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299828 | 0.89 | ALOX5 (0.36) | FFAR1ALOX5GRM5 | |
| SCHEMBL9299977 | 0.87 | ALOX5 (0.39) | FFAR1ALOX5PTGS1PTGS2GRM5 | |
| SCHEMBL9300627 | 0.86 | ALOX5 (0.45) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9299121 | 0.81 | ACACB (0.41) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9299297 | 0.76 | ALOX5 (0.37) | FFAR1ALOX5GRM5 | |
| SCHEMBL9192556 | 0.76 | ALOX5 (0.45) | FFAR1ALOX5PTGS1PTGS2GRM5 | |
| SCHEMBL9299307 | 0.74 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9298814 | 0.72 | ALOX5 (0.51) | FFAR1ALOX5PTGS1PTGS2 | |
| SCHEMBL9299666 | 0.72 | PTGES (0.44) | ALOX5PTGS1PTGS2GRM5 | |
| SCHEMBL9300259 | 0.72 | ACHE (0.39) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |