Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299121 | 0.92 | ACACB (0.41) | ACHEACACBL3MBTL1NR1H3ALDH1A1 | |
| SCHEMBL9299307 | 0.84 | ALOX5 (0.41) | PTGESALOX5 | |
| SCHEMBL9299828 | 0.81 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL9299028 | 0.80 | PTGES (0.45) | KDM4EPTGESALOX5 | |
| SCHEMBL9299238 | 0.79 | ACACB (0.46) | ACHEACACBL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9299660 | 0.79 | PTGES (0.45) | L3MBTL1PTGESALOX5 | |
| SCHEMBL9300599 | 0.76 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1MAPTPTGESALOX5 | |
| SCHEMBL9298923 | 0.76 | ACHE (0.41) | ACHEACACBBCHELMNAMEN1 | |
| SCHEMBL9300627 | 0.75 | ALOX5 (0.45) | PTGESALOX5MEN1KMT2A | |
| SCHEMBL9476259 | 0.74 | PTGES (0.58) | PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |