Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300259 | 0.92 | ACHE (0.39) | ACACBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9299238 | 0.88 | ACACB (0.46) | ACACBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9300627 | 0.84 | ALOX5 (0.45) | MEN1KMT2AALOX5PTGS1PTGS2 | |
| SCHEMBL9299727 | 0.81 | FFAR1 (0.38) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9300204 | 0.77 | PTGES (0.46) | ACACBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9299960 | 0.76 | ACACB (0.43) | ACACBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9299307 | 0.75 | ALOX5 (0.41) | ALOX5PTGES | |
| SCHEMBL9299666 | 0.73 | PTGES (0.44) | ALOX5PTGS1PTGS2PTGES | |
| SCHEMBL9197316 | 0.72 | PTGES (0.59) | ACACBALOX5PTGS1PTGS2PTGES | |
| SCHEMBL9299828 | 0.72 | ALOX5 (0.36) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |