Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301424 | 0.90 | ADRA1A (0.45) | CYP2D6CYP2C19MEN1KMT2AADRA1A | |
| SCHEMBL9302364 | 0.90 | EPHX2 (0.46) | MGLLUBE2MDCUN1D1CYP2D6CYP2C19 | |
| SCHEMBL9301904 | 0.87 | ADRA1A (0.51) | MGLLUBE2MDCUN1D1CYP2D6CYP2C19 | |
| SCHEMBL9302003 | 0.85 | ADRA1D (0.60) | MGLLADRA1AADRA1DADRA1B | |
| SCHEMBL9302459 | 0.81 | CXCR4 (0.54) | CYP2D6CYP2C19ADRA1AADRA1DADRA1B | |
| SCHEMBL9302183 | 0.77 | CYP2D6 (0.44) | MGLLUBE2MDCUN1D1ADRB2CYP2D6 | |
| SCHEMBL9301815 | 0.73 | ADRA1D (0.63) | ADRA1AADRA1DADRA1B | |
| SCHEMBL9302076 | 0.73 | EPHX2 (0.48) | MGLLUBE2MDCUN1D1HSD11B1MEN1 | |
| SCHEMBL9302313 | 0.73 | ADRA1D (0.57) | ADRA1AADRA1DADRA1B | |
| SCHEMBL9302494 | 0.73 | ADRA1A (0.49) | CYP2D6CYP2C19MEN1KMT2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |