Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302549 | 0.78 | LMNA (0.43) | NISCHADRA1ATP53CYP1A2CYP2D6 | |
| SCHEMBL9301877 | 0.74 | BACE1 (0.43) | MEN1KMT2A | |
| SCHEMBL9302452 | 0.73 | KDM4E (0.44) | TP53 | |
| SCHEMBL9302546 | 0.72 | SIGMAR1 (0.46) | — | |
| SCHEMBL9302494 | 0.66 | ADRA1A (0.49) | NISCHADRA1ATP53CYP1A2CYP3A4 | |
| SCHEMBL24214454 | 0.63 | NISCH (0.46) | NISCHADRA1ATP53CYP1A2CYP3A4 | |
| SCHEMBL20217195 | 0.60 | SMYD3 (0.49) | — | |
| SCHEMBL6097642 | 0.60 | ADRA1A (0.45) | NISCHADRA1ATP53CYP1A2CYP3A4 | |
| SCHEMBL10857472 | 0.59 | LMNA (0.42) | NISCHADRA1ATP53CYP1A2CYP2D6 | |
| SCHEMBL14367876 | 0.57 | ADRA1A (0.51) | NISCHADRA1ATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |