Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302484 | 0.78 | NISCH (0.39) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL10857472 | 0.77 | LMNA (0.42) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9301405 | 0.75 | ACHE (0.46) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9301653 | 0.74 | ACHE (0.47) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9303117 | 0.74 | LTA4H (0.48) | MAPT | |
| SCHEMBL9302321 | 0.74 | ATM (0.42) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL9301293 | 0.73 | LMNA (0.46) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9302654 | 0.72 | EPHX2 (0.45) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9301121 | 0.72 | ACHE (0.45) | MAPT | |
| SCHEMBL10852007 | 0.72 | LMNA (0.40) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |