Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301877 | 0.90 | BACE1 (0.43) | CXCR4DRD4DRD2DRD3 | |
| SCHEMBL9302546 | 0.87 | SIGMAR1 (0.46) | KDM4EALDH1A1MAPTSIGMAR1DRD4 | |
| SCHEMBL9302817 | 0.84 | AIMP2 (0.53) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL9302183 | 0.80 | CYP2D6 (0.44) | ALDH1A1L3MBTL1TP53 | |
| SCHEMBL9302459 | 0.76 | CXCR4 (0.54) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL9302484 | 0.73 | NISCH (0.39) | TP53 | |
| SCHEMBL9301121 | 0.73 | ACHE (0.45) | MAPTSIGMAR1CXCR4DRD4AIMP2 | |
| SCHEMBL9301593 | 0.71 | SIGMAR1 (0.48) | KDM4EALDH1A1MAPTSIGMAR1DRD4 | |
| SCHEMBL9301861 | 0.71 | BACE1 (0.49) | ALDH1A1CXCR4DRD4DRD2DRD3 | |
| SCHEMBL9301890 | 0.70 | L3MBTL1 (0.46) | KDM4EALDH1A1MAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |