Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 6/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302321 | 0.88 | ATM (0.42) | KMT2AALDH1A1CYP2A13LTA4HSIGMAR1 | |
| SCHEMBL9303117 | 0.85 | LTA4H (0.48) | LTA4HMAPTMAPK1 | |
| SCHEMBL9301121 | 0.82 | ACHE (0.45) | ACHECXCR4LTA4HHTR1ASIGMAR1 | |
| SCHEMBL9302817 | 0.80 | AIMP2 (0.53) | ALDH1A1CXCR4LTA4HHTR1ASIGMAR1 | |
| SCHEMBL9301593 | 0.78 | SIGMAR1 (0.48) | ALDH1A1LTA4HHTR1ASIGMAR1MAPT | |
| SCHEMBL9300946 | 0.78 | NPC1 (0.52) | ACHEKMT2AALDH1A1LTA4HSIGMAR1 | |
| SCHEMBL9302778 | 0.77 | SIGMAR1 (0.46) | ALDH1A1LTA4HSIGMAR1LMNAMAPT | |
| SCHEMBL9302549 | 0.74 | LMNA (0.43) | KMT2AALDH1A1LMNANPC1MAPT | |
| SCHEMBL9301658 | 0.74 | ADRA1D (0.64) | ACHECXCR4HTR1A | |
| SCHEMBL9301405 | 0.73 | ACHE (0.46) | ACHEKMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |