Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301293 | 0.93 | LMNA (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL9302303 | 0.90 | EPHX2 (0.47) | ALDH1A1SMN1; SMN2LMNANPSR1KMT2A | |
| SCHEMBL9301986 | 0.89 | CYP2D6 (0.46) | ALDH1A1CYP2C19KMT2AL3MBTL1POLB | |
| SCHEMBL9301807 | 0.87 | TSHR (0.45) | ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9301620 | 0.87 | RBP4 (0.48) | ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL9302654 | 0.85 | EPHX2 (0.45) | ALDH1A1SMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL9301418 | 0.82 | ACHE (0.43) | ACHEALDH1A1SMN1; SMN2LMNAEPHX1 | |
| SCHEMBL7435319 | 0.77 | EPHX1 (0.47) | ACHEALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9302070 | 0.76 | EPHX2 (0.47) | ALDH1A1LMNAKMT2AKDM4EEPHX2 | |
| SCHEMBL9302730 | 0.75 | EPHX2 (0.51) | ALDH1A1LMNAKMT2AKDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |