Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301405 | 0.85 | ACHE (0.46) | EPHX2KDM4EKMT2ACYP2C19ALDH1A1 | |
| SCHEMBL9301293 | 0.83 | LMNA (0.46) | EPHX2MEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL9302303 | 0.80 | EPHX2 (0.47) | EPHX2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9301807 | 0.80 | TSHR (0.45) | KDM4EMEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL9301986 | 0.80 | CYP2D6 (0.46) | MEN1KMT2ACYP2C19ALDH1A1HSD11B1 | |
| SCHEMBL9301620 | 0.79 | RBP4 (0.48) | MEN1KMT2AALDH1A1HSD11B1MGLL | |
| SCHEMBL9302321 | 0.78 | ATM (0.42) | KDM4EKMT2AALDH1A1MAPK1MAPT | |
| SCHEMBL9302670 | 0.73 | ADRA1D (0.60) | CYP2C9CYP2C19MAPK14ALDH1A1MAPK1 | |
| SCHEMBL13503788 | 0.73 | KDM4E (0.61) | EPHX2KDM4EMEN1KMT2ACYP2C9 | |
| SCHEMBL9302549 | 0.72 | LMNA (0.43) | KDM4EMEN1KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |