Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.52 |
| ▸ | CA2 | P00918 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 10/20 | 0.52 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL5847292 | 1.00 | CA12 (0.52) | CA12CA2CA9CA1CA14 | |
| SCHEMBL3171668 | 0.94 | CA12 (0.52) | CA12CA2CA9CA1CA14 | |
| SCHEMBL5846996 | 0.94 | CA12 (0.52) | CA12CA2CA9CA1CA14 | |
| Potassium Ion SCHEMBL1538011 | 0.90 | LMNA (0.48) | CA12CA2CA9CA1CA14 | |
| Potassium Ion SCHEMBL2501557 | 0.89 | CA12 (0.60) | CA12CA2CA9CA1CA14 | |
| Potassium Ion SCHEMBL29427233 | 0.85 | PTGS2 (0.42) | CA12CA2CA9CA1CA14 | |
| SCHEMBL8662029 | 0.84 | CA12 (0.60) | CA12CA2CA9CA1CA14 | |
| SCHEMBL11327611 | 0.84 | CA12 (0.60) | CA12CA2CA9CA1CA14 | |
| SCHEMBL11746260 | 0.84 | CA12 (0.60) | CA12CA2CA9CA1CA14 | |
| SCHEMBL19953365 | 0.83 | LMNA (0.55) | CA12CA2CA9CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776497-B | Preparation method for constructing two-dimensional organic layer based on cation-pi interaction | 西北工业大学 | 2022-12-13 | — | — | CN | claimed |
| US-4633024-A | Process for producing aromatic hydroxy compound | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1986-12-30 | — | — | US | claimed |
| US-4465878-A | ALKALI FUSION OF 4,4*-DIPHENYLDISULFONIC ACID WITH POTASSIUM HYDROXIDE AND SULFATE | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-08-14 | — | — | US | claimed |
| CN-110776497-B | Preparation method for constructing two-dimensional organic layer based on cation-pi interaction | 西北工业大学 | 2022-12-13 | — | — | CN | disclosed |
| CN-110776497-B | Preparation method for constructing two-dimensional organic layer based on cation-pi interaction | 西北工业大学 | 2022-12-13 | — | — | CN | disclosed |
| EP-0479292-B1 | Process for producing aromatic hydroxy compound | KAWASAKI STEEL CO (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5322946-A | Reacting aromatic sulfonic acid or salt with alkali metal hydroxide in presence of surfactant | KAWASAKI STEEL CORPORATION (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0092772-B2 | PROCESS FOR PRODUCING AROMATIC HYDROXY COMPOUND | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0479292-A1 | Process for producing aromatic hydroxy compound | KAWASAKI STEEL CORPORATION (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4633024-A | Process for producing aromatic hydroxy compound | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1986-12-30 | — | — | US | disclosed |
| EP-0092772-B1 | PROCESS FOR PRODUCING AROMATIC HYDROXY COMPOUND | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-4465878-A | ALKALI FUSION OF 4,4*-DIPHENYLDISULFONIC ACID WITH POTASSIUM HYDROXIDE AND SULFATE | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-08-14 | — | — | US | disclosed |
| EP-0092772-A1 | Process for producing aromatic hydroxy compound | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1983-11-02 | — | — | EP | disclosed |