Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.52 |
| ▸ | CA2 | P00918 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 10/20 | 0.52 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9302660 | 1.00 | CA12 (0.52) | CA12CA2CA9CA1CA14 | |
| SCHEMBL3171668 | 0.94 | CA12 (0.52) | CA12CA2CA9CA1CA14 | |
| SCHEMBL5846996 | 0.94 | CA12 (0.52) | CA12CA2CA9CA1CA14 | |
| Potassium Ion SCHEMBL1538011 | 0.90 | LMNA (0.48) | CA12CA2CA9CA1CA14 | |
| Potassium Ion SCHEMBL2501557 | 0.89 | CA12 (0.60) | CA12CA2CA9CA1CA14 | |
| Potassium Ion SCHEMBL29427233 | 0.85 | PTGS2 (0.42) | CA12CA2CA9CA1CA14 | |
| SCHEMBL8662029 | 0.84 | CA12 (0.60) | CA12CA2CA9CA1CA14 | |
| SCHEMBL11327611 | 0.84 | CA12 (0.60) | CA12CA2CA9CA1CA14 | |
| SCHEMBL11746260 | 0.84 | CA12 (0.60) | CA12CA2CA9CA1CA14 | |
| SCHEMBL19953365 | 0.83 | LMNA (0.55) | CA12CA2CA9CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200174008-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION | 2020-06-04 | — | — | US | disclosed |
| US-10436790-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | WATERS TECHNOLOGIES CORPORATION (US) | 2019-10-08 | — | — | US | disclosed |
| US-10416166-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | WATERS TECHNOLOGIES CORPORATION (US) | 2019-09-17 | — | — | US | disclosed |
| EP-3309549-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | Waters Technologies Corporation (US) | 2018-04-18 | — | — | EP | disclosed |
| US-9772333-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | WATER TECHNOLOGIES CORPORATION (US) | 2017-09-26 | — | — | US | disclosed |
| EP-2675524-B1 | DEVICE AND METHOD FOR TREATMENT OF CELLS AND CELL TISSUE | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2990401-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MASS SPECTROMETRY SIGNALS | Waters Technologies Corporation (US) | 2016-03-02 | — | — | EP | disclosed |
| US-20140350263-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2014-11-27 | — | — | US | disclosed |
| US-20140242709-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140179011-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2014-06-26 | — | — | US | disclosed |
| US-7151623-B2 | Holographic data-storage medium | TESA SCRIBOS GMBH (DE) | 2006-12-19 | — | — | US | disclosed |
| US-6667830-B1 | Super-resolution microscope system and method for illumination | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350263-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | FUT5, FUT6, CSGALNACT1 | CA12 1360/4885CA2 4542/4885CA9 3505/4885 |
| US-10416166-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | FUT5, FUT6, CSGALNACT1 | CA12 1226/4885CA2 4302/4885CA9 3476/4885 |
| US-20200174008-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | FUT5, FUT6, CSGALNACT1 | CA12 1360/4885CA2 4542/4885CA9 3505/4885 |
| US-10436790-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | FUT5, FUT6, CSGALNACT1 | CA12 911/4885CA2 4544/4885CA9 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.