Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24371811 | 1.00 | ALDH1A1 (0.50) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL15304485 | 1.00 | ALDH1A1 (0.50) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL13021363 | 1.00 | ALDH1A1 (0.50) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL16576338 | 1.00 | ALDH1A1 (0.50) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL12482663 | 1.00 | ALDH1A1 (0.50) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL14816712 | 0.90 | ALDH1A1 (0.52) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL15444764 | 0.89 | ALDH1A1 (0.46) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL2480916 | 0.88 | UPP1 (0.47) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL2480919 | 0.88 | UPP1 (0.47) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL2480913 | 0.88 | UPP1 (0.47) | ALDH1A1POLBGAAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4667053-A2 | BETA-D-2'-DEOXY-2'ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| EP-3265102-B1 | BETA-D-2'-DEOXY-2'ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2025-08-20 | — | — | EP | disclosed |
| US-20250243235-A1 | Beta-D-2'-DEOXY-2'-alpha-FLUORO-2'-Beta-C-SUBSTITUTED-2-MODIFIED-N6- SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT | Atea Pharmaceuticals, Inc. (US) | 2025-07-31 | — | — | US | disclosed |
| EP-4526318-A1 | FLEX-NUCLEOSIDE ANALOGUES, NOVEL THERAPEUTICS AGAINST VIRUSES | University of Maryland, Baltimore County (US) | 2025-03-26 | — | — | EP | disclosed |
| US-20250092080-A1 | FLEX-NUCLEOSIDE ANALOGUES, NOVEL THERAPEUTICS AGAINST VIRUSES | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY | 2025-03-20 | — | — | US | disclosed |
| US-12084473-B2 | β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment | Atea Pharmaceuticals, Inc. (US) | 2024-09-10 | — | — | US | disclosed |
| US-20240226131-A1 | 2'-CHLORO-2'-FLUORO-N2-AMINO-N6-METHYLAMINO PURINE NUCLEOTIDES FOR FLAVIVIRUS TREATMENT | Atea Pharmaceuticals, Inc. (US) | 2024-07-11 | — | — | US | disclosed |
| US-11975016-B2 | 2′-substituted-N6-substituted purine nucleotides for RNA virus treatment | Atea Pharmaceuticals, Inc. (US) | 2024-05-07 | — | — | US | disclosed |
| US-20240002426-A1 | BETA-D-2'-DEOXY-2'-ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT | Atea Pharmaceuticals, Inc. (US) | 2024-01-04 | — | — | US | disclosed |
| WO-2023225042-A1 | FLEX-NUCLEOSIDE ANALOGUES, NOVEL THERAPEUTICS AGAINST VIRUSES | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2023-11-23 | — | — | WO | disclosed |
| US-20110015146-A1 | NUCLEOSIDE PHOSPHORAMIDATES | PHARMASSET, INC. (US) | 2011-01-20 | — | — | US | disclosed |
| US-20100286083-A1 | NUCLEOSIDE ANALOGS | PHARMASSET, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100286083-A1 | NUCLEOSIDE ANALOGS | PHARMASSET, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100279973-A1 | SYNTHESIS OF PURINE NUCLEOSIDES | PHARMASSET, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| WO-2010075549-A2 | NUCLEOSIDE PHOSPHORAMIDATES | PHARMASSET, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010075554-A1 | SYNTHESIS OF PURINE NUCLEOSIDES | PHARMASSET, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010075517-A2 | NUCLEOSIDE ANALOGS | PHARMASSET, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010075517-A2 | NUCLEOSIDE ANALOGS | PHARMASSET, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| US-20100081628-A1 | NUCLEOSIDE CYCLICPHOSPHATES | PHARMASSET, INC. (US) | 2010-04-01 | — | — | US | disclosed |
| WO-2009152095-A2 | NUCLEOSIDE CYCLICPHOSPHATES | PHARMASSET, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279973-A1 | SYNTHESIS OF PURINE NUCLEOSIDES | PNP, NUDT1, TYMP | ALDH1A1 2131/4885POLB 266/4885GAA 916/4885 |
| US-20240226131-A1 | 2'-CHLORO-2'-FLUORO-N2-AMINO-N6-METHYLAMINO PURINE NUCLEOTIDES FOR FLAVIVIRUS TREATMENT | NSUN2, PNP, METTL3 | ALDH1A1 2538/4885POLB 1193/4885GAA 2836/4885 |
| US-20110015146-A1 | NUCLEOSIDE PHOSPHORAMIDATES | PNP, TYMP, NUDT14 | ALDH1A1 2155/4885POLB 150/4885GAA 407/4885 |
| US-12084473-B2 | β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment | NSUN2, PNP, NUDT1 | ALDH1A1 1295/4885POLB 130/4885GAA 1055/4885 |
| US-20250092080-A1 | FLEX-NUCLEOSIDE ANALOGUES, NOVEL THERAPEUTICS AGAINST VIRUSES | FLNA, PNP, SMCHD1 | ALDH1A1 4356/4885POLB 160/4885GAA 2490/4885 |
| US-11975016-B2 | 2′-substituted-N6-substituted purine nucleotides for RNA virus treatment | NSUN2, ADAR, NSUN3 | ALDH1A1 1890/4885POLB 333/4885GAA 1077/4885 |
| US-20250243235-A1 | Beta-D-2'-DEOXY-2'-alpha-FLUORO-2'-Beta-C-SUBSTITUTED-2-MODIFIED-N6- SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT | NSUN2, NUDT1, DCTD | ALDH1A1 1397/4885POLB 81/4885GAA 1102/4885 |
| US-20100081628-A1 | NUCLEOSIDE CYCLICPHOSPHATES | PNP, NUDT1, TYMP | ALDH1A1 3540/4885POLB 83/4885GAA 566/4885 |
| US-20240002426-A1 | BETA-D-2'-DEOXY-2'-ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT | NSUN2, NUDT1, DCTD | ALDH1A1 1397/4885POLB 81/4885GAA 1102/4885 |
| US-20100286083-A1 | NUCLEOSIDE ANALOGS | PNP, SAMHD1, HAVCR2 | ALDH1A1 931/4885POLB 77/4885GAA 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.