Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308116 | 0.85 | KMT2A (0.38) | MGLLL3MBTL1KDM4EALDH1A1KDM2B | |
| SCHEMBL9310079 | 0.83 | ALOX5 (0.45) | KDM4EALDH1A1KDM2B | |
| SCHEMBL29078315 | 0.75 | CES2 (0.50) | KDM4EALDH1A1KDM2BCHEK2NPC1 | |
| SCHEMBL8953658 | 0.74 | HSD11B1 (0.37) | MGLLKDM4EALDH1A1KDM2BHSD11B1 | |
| SCHEMBL8953741 | 0.74 | KMT2A (0.50) | ALDH1A1KDM2B | |
| SCHEMBL9309515 | 0.73 | SLC6A2 (0.32) | — | |
| SCHEMBL8953563 | 0.72 | MGLL (0.50) | MGLLALDH1A1HSD11B1CHEK2 | |
| SCHEMBL9309969 | 0.70 | ALOX5 (0.43) | L3MBTL1KDM4EALDH1A1KDM2BHSD11B1 | |
| SCHEMBL20522128 | 0.70 | HCAR1 (0.44) | MGLLALDH1A1HSD11B1CHEK2RAB9A | |
| SCHEMBL8953638 | 0.67 | HRH3 (0.40) | ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |