Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 4/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314265 | 0.87 | KEAP1 (0.50) | HPGDSBRS3AOC3CAPN1CYP1A2 | |
| SCHEMBL9314201 | 0.81 | HDAC3 (0.53) | HPGDSBRS3AOC3CAPN1CYP1A2 | |
| SCHEMBL7345076 | 0.79 | BRS3 (0.49) | HPGDSBRS3AOC3CAPN1KDM6B | |
| SCHEMBL7688678 | 0.77 | HPGDS (0.50) | HPGDSBRS3AOC3CAPN1 | |
| SCHEMBL8957090 | 0.75 | HRH1 (0.62) | TDP1HPGDSBRS3AOC3CAPN1 | |
| SCHEMBL8957140 | 0.74 | SLC7A5 (0.54) | HPGDSBRS3AOC3 | |
| SCHEMBL11552467 | 0.73 | HPGDS (0.50) | HPGDSBRS3AOC3CAPN1 | |
| SCHEMBL7846648 | 0.73 | MMP2 (0.51) | HPGDSBRS3AOC3CAPN1SMN1; SMN2 | |
| SCHEMBL30572 | 0.72 | TDP1 (0.77) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15524969 | 0.72 | TDP1 (0.77) | NPC1RAB9ATDP1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589975-A1 | NEW SELECTIVE AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992022537-A1 | NEW SELECTIVE AROMATASE INHIBITING 4(5)-IMIDAZOLES | Orion-Yhtymä Oy (FI) | 1992-12-23 | — | — | WO | disclosed |