Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | BRS3 | P32247 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345076 | 0.84 | BRS3 (0.49) | MMP2RNASEH1HPGDSBRS3CAPN1 | |
| SCHEMBL9314265 | 0.77 | KEAP1 (0.50) | MMP2HPGDSBRS3KDM4ESMN1; SMN2 | |
| SCHEMBL7688678 | 0.76 | HPGDS (0.50) | HPGDSBRS3CAPN1AOC3 | |
| SCHEMBL9314201 | 0.74 | HDAC3 (0.53) | HPGDSBRS3MAPTSMN1; SMN2CAPN1 | |
| SCHEMBL9314193 | 0.73 | HSD11B1 (0.48) | HPGDSBRS3MAPTSMN1; SMN2CAPN1 | |
| SCHEMBL8957140 | 0.73 | SLC7A5 (0.54) | HPGDSBRS3HSD17B10AOC3 | |
| SCHEMBL11552467 | 0.72 | HPGDS (0.50) | HPGDSBRS3CAPN1KMT2AAOC3 | |
| SCHEMBL6239887 | 0.72 | CYP4F2 (0.59) | KDM4EALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL8957153 | 0.71 | MMP2 (0.44) | MMP2RNASEH1HPGDSBRS3KDM4E | |
| SCHEMBL8957090 | 0.71 | HRH1 (0.62) | HPGDSBRS3KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140942-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039130-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2000-07-06 | — | — | WO | disclosed |