Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | BRS3 | P32247 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314265 | 0.91 | KEAP1 (0.50) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL7345076 | 0.83 | BRS3 (0.49) | BRS3HPGDSAOC3CAPN1 | |
| SCHEMBL9314193 | 0.81 | HSD11B1 (0.48) | SMN1; SMN2BRS3MAPTCYP1A2HPGDS | |
| SCHEMBL7688678 | 0.78 | HPGDS (0.50) | BRS3HPGDSAOC3CAPN1 | |
| SCHEMBL11552467 | 0.78 | HPGDS (0.50) | BRS3HPGDSAOC3CAPN1 | |
| SCHEMBL8957090 | 0.76 | HRH1 (0.62) | SMN1; SMN2BRS3MAPTHPGDSAOC3 | |
| SCHEMBL8957140 | 0.75 | SLC7A5 (0.54) | BRS3HPGDSAOC3 | |
| SCHEMBL7846648 | 0.74 | MMP2 (0.51) | SMN1; SMN2BRS3MAPTHPGDSAOC3 | |
| Hydrochloric Acid SCHEMBL8368581 | 0.74 | BRS3 (0.52) | BRS3TBXAS1 | |
| SCHEMBL13851686 | 0.72 | HDAC1 (0.84) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589975-A1 | NEW SELECTIVE AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992022537-A1 | NEW SELECTIVE AROMATASE INHIBITING 4(5)-IMIDAZOLES | Orion-Yhtymä Oy (FI) | 1992-12-23 | — | — | WO | disclosed |