Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322401 | 0.95 | GAA (0.40) | THRATHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL9324758 | 0.89 | LTA4H (0.42) | THRATHRBGAATP53SMN1; SMN2 | |
| SCHEMBL9321412 | 0.81 | SMN1; SMN2 (0.48) | GNAI3GNAO1GNAI1FPR3FPR2 | |
| SCHEMBL24633509 | 0.80 | TP53 (0.47) | THRATHRBGAATP53SMN1; SMN2 | |
| SCHEMBL9323677 | 0.79 | SMN1; SMN2 (0.39) | GNAI3GNAO1GNAI1FPR3FPR2 | |
| SCHEMBL9322356 | 0.78 | BCHE (0.47) | GNAI3GNAO1GNAI1TP53SMN1; SMN2 | |
| SCHEMBL9324718 | 0.77 | HRH3 (0.45) | FPR3FPR2TP53SMN1; SMN2RAD52 | |
| SCHEMBL9323550 | 0.76 | TP53 (0.39) | FPR3FPR2TP53SMN1; SMN2 | |
| SCHEMBL9323743 | 0.76 | THRA (0.40) | THRATHRBGAATP53SMN1; SMN2 | |
| SCHEMBL9322390 | 0.76 | HRH3 (0.48) | FPR3FPR2TP53SMN1; SMN2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |