Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 8/20 | 0.30 |
| ▸ | CA2 known ✓ | P00918 | 8/20 | 0.30 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.30 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 7/20 | 0.30 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
| ▸ | CA3 | P07451 | 2/20 | 0.30 |
| ▸ | CA6 | P23280 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990151 | 0.84 | DNTT (0.33) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL1341341 | 0.76 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL6129344 | 0.76 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL1270093 | 0.76 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL15452912 | 0.75 | DNTT (0.34) | DNTT | |
| SCHEMBL6208628 | 0.74 | DNTT (0.36) | HPGDMAPK1DNTT | |
| SCHEMBL6209156 | 0.74 | DNTT (0.36) | HPGDMAPK1DNTT | |
| SCHEMBL6210762 | 0.74 | DNTT (0.36) | HPGDMAPK1DNTT | |
| SCHEMBL6210729 | 0.74 | DNTT (0.36) | HPGDMAPK1DNTT | |
| SCHEMBL6207650 | 0.74 | DNTT (0.36) | HPGDMAPK1DNTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265187-B1 | Detergent plus softener with imidazoline ingredient | PROCTER & GAMBLE (US) | 1994-03-09 | — | — | EP | claimed |
| US-4770815-A | ANIONIC SURFACTANTS; OPTIONALLY CONTAINING CLAYS, BUILDERS, CHELATING AGENTS AND-OR BLEACHING AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-13 | — | — | US | claimed |
| EP-0265187-A2 | Detergent plus softener with imidazoline ingredient | THE PROCTER & GAMBLE COMPANY (US) | 1988-04-27 | — | — | EP | claimed |
| EP-0265187-B1 | Detergent plus softener with imidazoline ingredient | PROCTER & GAMBLE (US) | 1994-03-09 | — | — | EP | disclosed |
| EP-0294892-B1 | CONDITIONING AGENTS AND COMPOSITIONS CONTAINING SAME | THE PROCTER & GAMBLE COMPANY (US) | 1993-08-18 | — | — | EP | disclosed |
| EP-0550087-A1 | Liquid automatic dishwashing composition | UNILEVER N.V. (NL) | 1993-07-07 | — | — | EP | disclosed |
| EP-0328205-B1 | CONDITIONING AGENT CONTAINING AMINE ION-PAIR COMPLEXES AND COMPOSITIONS THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 1993-05-12 | — | — | EP | disclosed |
| EP-0268324-B1 | ION-PAIR COMPLEX CONDITIONING AGENT AND COMPOSITIONS CONTAINING SAME | THE PROCTER & GAMBLE COMPANY (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5019280-A | Ion-pair complex conditioning agent with benzene sulfonate/alkyl benzene sulfonate anionic component and compositions containing same | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| US-4915854-A | FABRIC SOFTENERS, LAUNDERING | THE PROCTER & GAMBLE COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4861502-A | Conditioning agent containing amine ion-pair complexes and composiitons thereof | THE PROCTER & GAMBLE COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0328205-A2 | Conditioning agent containing amine ion-pair complexes and compositions thereof | THE PROCTER & GAMBLE COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0294892-A2 | Conditioning agents and compositions containing same | THE PROCTER & GAMBLE COMPANY (US) | 1988-12-14 | — | — | EP | disclosed |
| US-4770815-A | ANIONIC SURFACTANTS; OPTIONALLY CONTAINING CLAYS, BUILDERS, CHELATING AGENTS AND-OR BLEACHING AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0268324-A2 | Ion-pair complex conditioning agent and compositions containing same | THE PROCTER & GAMBLE COMPANY (US) | 1988-05-25 | — | — | EP | disclosed |
| EP-0265187-A2 | Detergent plus softener with imidazoline ingredient | THE PROCTER & GAMBLE COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |