Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 2/20 | 0.32 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.31 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 5/20 | 0.34 |
| ▸ | CES1 | P23141 | 5/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129344 | 1.00 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL1341341 | 1.00 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL17746174 | 0.87 | PRKCA (0.35) | TSHRCES2CES1PRKCAPPARG | |
| SCHEMBL17748986 | 0.87 | PRKCA (0.35) | TSHRCES2CES1PRKCAPPARG | |
| SCHEMBL6129333 | 0.77 | CA2 (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL9325236 | 0.76 | RECQL (0.42) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL27607378 | 0.69 | RECQL (0.36) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL5444633 | 0.66 | RECQL (0.37) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL27589475 | 0.65 | HSD17B3 (0.39) | TSHRPPARGPPARDPPARA | |
| SCHEMBL29398892 | 0.62 | RECQL (0.76) | RECQLGLAHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323437-B2 | Process for producing a bleaching activator composition | KAO CORPORATION (JP) | 2008-01-29 | — | — | US | claimed |
| EP-2284251-B1 | Alkaline protease with an enhanced specific activity to casein | KAO CORP (JP) | 2014-04-30 | — | — | EP | disclosed |
| EP-1347044-B1 | Alkaline protease | KAO CORP (JP) | 2013-12-04 | — | — | EP | disclosed |
| EP-2284251-A1 | Alkaline protease | Kao Corporation (JP) | 2011-02-16 | — | — | EP | disclosed |
| US-7811076-B2 | Alkaline protease and washing and cleaning products containing said novel alkaline protease | HENKEL AG & CO. KGAA (DE) | 2010-10-12 | — | — | US | disclosed |
| US-7776578-B2 | Alkaline protease | KAO CORPORATION (JP) | 2010-08-17 | — | — | US | disclosed |
| US-20080177040-A1 | ALKALINE PROTEASE | KAO CORPORATION (JP) | 2008-07-24 | — | — | US | disclosed |
| US-7368273-B2 | Alkaline protease | KAO CORPORATION (JP) | 2008-05-06 | — | — | US | disclosed |
| US-7323437-B2 | Process for producing a bleaching activator composition | KAO CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| EP-1548097-B1 | Process for producing a bleaching activator composition | KAO CORP (JP) | 2007-05-16 | — | — | EP | disclosed |
| US-20070010417-A1 | Novel alkaline protease and washing and cleaning products containing said novel alkaline protease | B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (DE) | 2007-01-11 | — | — | US | disclosed |
| US-20050170984-A1 | Process for producing a bleaching activator composition | KAO CORPORATION (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1548097-A1 | Process for producing a bleaching activator composition | KAO CORPORATION (JP) | 2005-06-29 | — | — | EP | disclosed |
| US-20040002432-A1 | Alkaline protease | KAO CORPORATION (JP) | 2004-01-01 | — | — | US | disclosed |
| EP-1347044-A2 | Alkaline protease | Kao Corporation (JP) | 2003-09-24 | — | — | EP | disclosed |
| WO-2001046366-A1 | DETERGENT COMPOSITIONS HAVING A POLYPHOSPHATE SALT | THE PROCTER & GAMBLE COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |
| EP-1047760-A1 | GRANULAR COMPOSITIONS HAVING IMPROVED DISSOLUTION | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-2000040686-A1 | DETERGENT COMPOSITIONS HAVING A PROTEIN | THE PROCTER & GAMBLE COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |
| WO-1999036494-A1 | GRANULAR COMPOSITIONS HAVING IMPROVED DISSOLUTION | THE PROCTER & GAMBLE COMPANY (US) | 1999-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010417-A1 | Novel alkaline protease and washing and cleaning products containing said novel alkaline protease | ANPEP, TMPRSS15, DNASE1 | PPARG 4822/4885CA1 429/4885CA2 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.