Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | TOP1 | P11387 | 3/20 | 0.71 |
| ▸ | TOP2A | P11388 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | TERT | O14746 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.65 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551571 | 0.91 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14669385 | 0.89 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14906738 | 0.88 | NPBWR1 (0.58) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14906542 | 0.87 | CBFB (0.58) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14892811 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14656343 | 0.85 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL24233364 | 0.85 | MAPT (0.63) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14399402 | 0.84 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL18595033 | 0.84 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14906587 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475443-B1 | METHODS AND COMPOSITIONS FOR DETECTING OR MEASURING CASPASES OR APOPTOSIS | LIFE TECHNOLOGIES CORP (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2022021981-A1 | DI-(BENZIMIDAZOLE)-1, 2, 3-TRIAZOLE DERIVATIVE AND PREPARATION THEREFOR AND USE THEREOF | 中南大学湘雅二医院 | 2022-02-03 | — | — | WO | disclosed |
| US-20210324198-A1 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | Life Technologies Corporation | 2021-10-21 | — | — | US | disclosed |
| EP-3833715-A2 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | Life Technologies Corporation (US) | 2021-06-16 | — | — | EP | disclosed |
| WO-2021105887-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-06-03 | — | — | WO | disclosed |
| US-20210155657-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-05-27 | — | — | US | disclosed |
| US-10941435-B2 | Methods and compositions for detecting or measuring caspases or apoptosis | Life Technologies Corporation (US) | 2021-03-09 | — | — | US | disclosed |
| WO-2020033681-A2 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | Life Technologies Corporation (US) | 2020-02-13 | — | — | WO | disclosed |
| US-20190309341-A1 | METHODS AND COMPOSITIONS FOR DETECTING OR MEASURING CASPASES OR APOPTOSIS | Life Technologies Corporation (US) | 2019-10-10 | — | — | US | disclosed |
| EP-3475443-A1 | METHODS AND COMPOSITIONS FOR DETECTING OR MEASURING CASPASES OR APOPTOSIS | Life Technologies Corporation (US) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017223147-A1 | METHODS AND COMPOSITIONS FOR DETECTING OR MEASURING CASPASES OR APOPTOSIS | Life Technologies Corporation (US) | 2017-12-28 | — | — | WO | disclosed |
| WO-2011008985-A2 | METHODS AND COMPOSITIONS FOR IMPROVED DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-20 | — | — | WO | disclosed |
| WO-2007016455-A2 | COMPOSITIONS AND METHODS USING AMINOGLYCOSIDES TO BIND DNA AND RNA | CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155657-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | ADAR, SSBP1, POLRMT | ALDH1A1 4165/4885SMN1; SMN2 1103/4885TOP1 237/4885 |
| US-10941435-B2 | Methods and compositions for detecting or measuring caspases or apoptosis | CASP3, CASP5, CASP1 | ALDH1A1 4307/4885SMN1; SMN2 3701/4885TOP1 199/4885 |
| US-20210324198-A1 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | SRI, SI, IK | ALDH1A1 1849/4885SMN1; SMN2 2012/4885TOP1 1255/4885 |
| US-20190309341-A1 | METHODS AND COMPOSITIONS FOR DETECTING OR MEASURING CASPASES OR APOPTOSIS | CASP3, CASP5, CASP7 | ALDH1A1 4303/4885SMN1; SMN2 3636/4885TOP1 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.