Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364872 | 0.93 | NAAA (0.38) | LNPEPCTSLCTSSERAP2SLC15A1 | |
| SCHEMBL9699796 | 0.81 | CTSK (0.41) | CTSLCTSSNAAAALDH1A1CYP3A4 | |
| SCHEMBL9369693 | 0.81 | CTSL (0.44) | LNPEPCTSLCTSSERAP2SLC15A1 | |
| SCHEMBL9699824 | 0.76 | SLC15A1 (0.41) | CTSLCTSSSLC15A1NAAAALDH1A1 | |
| SCHEMBL7476658 | 0.73 | SLC15A1 (0.46) | CTSLCTSSSLC15A1SLC1A3SLC1A1 | |
| SCHEMBL9364548 | 0.72 | CTSK (0.45) | CTSLCTSSSLC15A1SLC1A3SLC1A1 | |
| SCHEMBL9012148 | 0.69 | CTSB (0.44) | CTSLCTSSCYP3A4CTSBCTSK | |
| SCHEMBL5501379 | 0.67 | CTSL (0.61) | CTSLCTSSCTSBCTSK | |
| SCHEMBL7266217 | 0.67 | ALDH1A1 (0.52) | LNPEPCTSLCTSSERAP2ALDH1A1 | |
| SCHEMBL7266221 | 0.67 | ALDH1A1 (0.52) | LNPEPCTSLCTSSERAP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538396-A4 | — | — | 1994-04-13 | — | — | EP | disclosed |
| EP-0538396-A1 | INHIBITORS OF RETROVIRAL PROTEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000948-A1 | INHIBITORS OF RETROVIRAL PROTEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |